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Anti-Glucose Transporter GLUT4/SLC2A4 Antibody Picoband® Europäischer Partner

ArtNr BOS-PB9109
Hersteller Boster
Menge 100 ug/vial
Kategorie
Typ Antibody Polyclonal
Format Lyophilized
Applikationen WB, IHC
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host Rabbit
Isotype IgG
Sensitivity <5pg/ml
Citations 1. James DE, Brown R, Navarro J, Pilch PF (May 1988). "Insulin-regulatable tissues express a unique insulin-sensitive glucose transport protein". Nature 333 (6169): 183–5.
2. James DE, Strube M, Mueckler M (March 1989). "Molecular cloning and characterization of an insulin-regulatable glucose transporter". Nature 338 (6210): 83–7.
3. Birnbaum MJ (April 1989). “Identification of a novel gene encoding an insulin-responsive glucose transporter protein”. Cell 57 (2): 305–15.
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias Solute carrier family 2, facilitated glucose transporter member 4;Glucose transporter type 4, insulin-responsive;GLUT-4;SLC2A4;GLUT4;
Similar products Solute carrier family 2, insulin-responsive antibody, Glucose transporter GLUT 4 antibody, Glucose transporter type 4 antibody, Glucose transporter type 4 insulin responsive antibody, GLUT 4 antibody, GLUT-4 antibody, GLUT4 antibody, GTR4_HUMAN antibody, kug antibody, SLC 2A4 antibody, SLC2A4 antibody, facilitated glucose transporter member 4 antibody, solute carrier family 2 (facilitated glucose transporter) member 4 antibody
Lieferbar
Manufacturer - Category
Primary Antibodies
Manufacturer - Isotype
Rabbit IgG
Storage Conditions
Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
55 kDa
Calculated Molecular weight
54787 MW
Clonality
Polyclonal
Application Details
Immunohistochemistry (Frozen Section), 0.5-1?g/ml, Mouse, Rat, -
Immunohistochemistry (Paraffin-embedded Section), 0.5-1?g/ml, Human, Mouse, Rat, By Heat
Western blot, 0.1-0.5?g/ml, Rat, Human
Manufacturer - Gene Name
SLC2A4
Gene Full Name
Solute carrier family 2, facilitated glucose transporter member 4
Manufacturer - Specificity
No cross reactivity with other proteins.
Background
GLUT4, also known as SLC2A4 or solute carrier family 2 (facilitated glucose transporter) member 4, is a protein that in humans is encoded by the GLUT4 gene. It is mapped to 17p13.1. This gene is a member of the solute carrier family 2 (facilitated glucose transporter) family and encodes a protein that functions as an insulin-regulated facilitative glucose transporter. In the absence of insulin, this integral membrane protein is sequestered within the cells of muscle and adipose tissue. Within minutes of insulin stimulation, the protein moves to the cell surface and begins to transport glucose across the cell membrane. Mutations in this gene have been associated with noninsulin-dependent diabetes mellitus (NIDDM).
Immunogen
E.coli-derived human GLUT4 recombinant protein (Position: N333-D509). Human GLUT4 shares 97% amino acid (aa) sequence identity with mouse GLUT4.
Contents
Each vial contains 5 mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05 mg NaN3.
Purification
Immunogen affinity purified.
Reconstitution
Add 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Concentration
Adding 0.2 ml of distilled water will yield a concentration of 500 ?g/ml.
Manufacturer - Research Category
Cardiovascular, Energy Metabolism, Energy Transfer Pathways, Epigenetics and Nuclear Signaling, Metabolic Signaling Pathways, Metabolism, Pathways and Processes, Signal Transduction, Transcription, Transcription Factors
Protein Name
Solute carrier family 2, facilitated glucose transporter member 4
Protein Function
Insulin-regulated facilitative glucose transporter.
Subcellular Localization
Cell membrane; Multi-pass membrane protein. Endomembrane system; Multi-pass membrane protein. Cytoplasm, perinuclear region. Localizes primarily to the perinuclear region, undergoing continued recycling to the plasma membrane where it is rapidly reinternalized. The dileucine internalization motif is critical for intracellular sequestration.
Description
Boster Bio Anti-Glucose Transporter GLUT4/SLC2A4 Antibody Picoband® catalog # PB9109. Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Tissue Specificity
Skeletal and cardiac muscles; brown and white fat.
Sequence Similarities
Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ug/vial
Lieferbar: In stock
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