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Anti-CYP2A6V2 Antibody

Anti-CYP2A6V2 Antibody

ArtNr	BOS-A00947
Hersteller	Boster
Menge	100 ul
Kategorie	Food Safety Mycotoxins Antibodies Western Blot Primary Antibodies
Typ	Antibody
Format	Liquid
Applikationen	WB
Specific against	Human (Homo sapiens)
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Cytochrome P450 2A6;1.14.13.-;1,4-cineole 2-exo-monooxygenase;CYPIIA6;Coumarin 7-hydroxylase;Cytochrome P450 IIA3;Cytochrome P450 (I);CYP2A6;CYP2A3;
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Manufacturer - Category	Primary Antibodies
Storage Conditions	Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight	56501 MW
Clonality	Polyclonal
Application Details	Western blotting: 1:500~1:3000
Manufacturer - Gene Name	CYP2A6
Gene Full Name	Cytochrome P450 2A6
Background	Metabolizes several precarcinogens, drugs, and solvents to reactive metabolites. Inactivates a number of drugs and xenobiotics and also bioactivates many xenobiotic substrates to their hepatotoxic or carcinogenic forms. Fernandez-Salguero P., Am. J. Hum. Genet. 57:651-660(1995).
Immunogen	Synthesized peptide derived from N-terminal of human CYP2A6V2.
Contents	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration	1 mg/ml
Manufacturer - Research Category	Drug Metabolism, Lipases, Lipid and Lipoprotein Metabolism, Lipid Metabolism, Lipids/Lipoproteins, Metabolic Signaling Pathways, Metabolism, Mitochondrial Metabolism, Pathways and Processes, Signal Transduction
Protein Function	Exhibits a high coumarin 7-hydroxylase activity. Can act in the hydroxylation of the anti-cancer drugs cyclophosphamide and ifosphamide. Competent in the metabolic activation of aflatoxin B1. Constitutes the major nicotine C-oxidase. Acts as a 1, 4- cineole 2-exo-monooxygenase. Possesses low phenacetin O- deethylation activity.
Subcellular Localization	Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
Short Description	Boster Bio Anti-CYP2A6V2 Antibody (Catalog # A00947). Tested in WB applications. This antibody reacts with Human.
Description	Boster Bio Anti-CYP2A6V2 Antibody (Catalog # A00947). Tested in WB applications. This antibody reacts with Human.
Tissue Specificity	Liver.

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BOS-A00947-datasheet.pdf

BOS-A00947-safety-datasheet.pdf