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Anti-CYP2A6V2 Antibody

Anti-CYP2A6V2 Antibody

Manufacturer	Boster
Category	Food Safety Mycotoxins Antibodies Western Blot Primary Antibodies
Type	Antibody
Specific against	Human
Format	Liquid
Applications	WB
Amount	100ul
Host	Rabbit
Item no.	BOS-A00947
eClass 6.1	32160702
eClass 9.0	32160702
Available
Manufacturers Product Category	Primary Antibodies
Manufacturers Research Category	Drug Metabolism, Lipases, Lipid and Lipoprotein Metabolism, Lipid Metabolism, Lipids/Lipoproteins, Metabolic Signaling Pathways, Metabolism, Mitochondrial Metabolism, Pathways and Processes, Signal Transduction
Short Description	Boster Bio Anti-CYP2A6V2 Antibody (Catalog # A00947). Tested in WB applications. This antibody reacts with Human.
Description	Boster Bio Anti-CYP2A6V2 Antibody (Catalog # A00947). Tested in WB applications. This antibody reacts with Human.
Background	Metabolizes several precarcinogens, drugs, and solvents to reactive metabolites. Inactivates a number of drugs and xenobiotics and also bioactivates many xenobiotic substrates to their hepatotoxic or carcinogenic forms. Fernandez-Salguero P., Am. J. Hum. Genet. 57:651-660(1995).
Gene Name	CYP2A6
Clonality	Polyclonal
Concentration	1 mg/ml
Contents	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Application Details	Western blotting: 1:500~1:3000
Immunogen	Synthesized peptide derived from N-terminal of human CYP2A6V2.
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Gene Full Name	Cytochrome P450 2A6
Molecular Weight	56501 MW
Protein Function	Exhibits a high coumarin 7-hydroxylase activity. Can act in the hydroxylation of the anti-cancer drugs cyclophosphamide and ifosphamide. Competent in the metabolic activation of aflatoxin B1. Constitutes the major nicotine C-oxidase. Acts as a 1, 4- cineole 2-exo-monooxygenase. Possesses low phenacetin O- deethylation activity..
Subcellular Localization	Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
Tissue Specificity	Liver..

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

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Amount: 100ul

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Delivery expected until 5/30/2024