Anti-GABRB1(Ab-434) Antibody

Boster Bio Anti-GABRB1(Ab-434) Antibody (Catalog # A04752). Tested in WB, IHC applications. This antibody reacts with Human, Mouse, Rat.

The gamma-aminobutyric acid (GABA) A receptor is a multisubunit chloride channel that mediates the fastest inhibitory synaptic transmission in the central nervous system. This gene encodes GABA A receptor, beta 1 subunit. It is mapped to chromosome 4p12 in a cluster comprised of genes encoding a 4, a 2 and gamma 1 subunits of the GABA A receptor. Alteration of this gene is implicated in the pathogenetics of schizophrenia.



Collins AL, et al. (2006) Neurogenetics ; 7(3):167-174.

Ma DQ, et al. (2005) Am J Hum Genet ; 77(3):377-388.

Edenberg HJ, et al. (2004) Am J Hum Genet ; 74(4):705-714.

Polyclonal

Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Peptide sequence around aa.432~436 (R-A-S-Q-L) derived from Human GABRB1.

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

54235 MW

Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.