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Anti-GABRB1(Ab-434) Antibody

Anti-GABRB1(Ab-434) Antibody

Manufacturer	Boster
Category	Food Safety Histamines Neuroscience Neural Signaling Antibodies Western Blot Primary Antibodies
Type	Antibody
Specific against	Human, Mouse, Rat
Format	Liquid
Applications	WB, IHC
Amount	100ul
Host	Rabbit
Item no.	BOS-A04752
eClass 6.1	32160702
eClass 9.0	32160702
Available
Manufacturers Product Category	Primary Antibodies
Short Description	Boster Bio Anti-GABRB1(Ab-434) Antibody (Catalog # A04752). Tested in WB, IHC applications. This antibody reacts with Human, Mouse, Rat.
Description	Boster Bio Anti-GABRB1(Ab-434) Antibody (Catalog # A04752). Tested in WB, IHC applications. This antibody reacts with Human, Mouse, Rat.
Background	The gamma-aminobutyric acid (GABA) A receptor is a multisubunit chloride channel that mediates the fastest inhibitory synaptic transmission in the central nervous system. This gene encodes GABA A receptor, beta 1 subunit. It is mapped to chromosome 4p12 in a cluster comprised of genes encoding a 4, a 2 and gamma 1 subunits of the GABA A receptor. Alteration of this gene is implicated in the pathogenetics of schizophrenia. Collins AL, et al. (2006) Neurogenetics ; 7(3):167-174. Ma DQ, et al. (2005) Am J Hum Genet ; 77(3):377-388. Edenberg HJ, et al. (2004) Am J Hum Genet ; 74(4):705-714.
Gene Name	GABRB1
Clonality	Polyclonal
Concentration	1 mg/ml
Contents	Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Application Details	Predicted MW: 54kd Western blotting: 1:500~1:1000 IHC 1:50-1:200
Immunogen	Peptide sequence around aa.432~436 (R-A-S-Q-L) derived from Human GABRB1.
Purification	Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Storage	Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Gene Full Name	Gamma-aminobutyric acid receptor subunit beta-1
Molecular Weight	54235 MW
Protein Function	Component of the heteropentameric receptor for GABA, the major inhibitory neurotransmitter in the vertebrate brain. Functions also as histamine receptor and mediates cellular responses to histamine. Functions as receptor for diazepines and various anesthetics, such as pentobarbital; these are bound at a separate allosteric effector binding site. Functions as ligand- gated chloride channel (By similarity)..
Subcellular Localization	Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.

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Amount: 100ul

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Delivery expected until 5/30/2024