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Anti-CC14A CDC14A Antibody Europäischer Partner

ArtNr BOS-A05617
Hersteller Boster
Menge 100 ul
Kategorie
Typ Antibody
Format Liquid
Applikationen WB
Specific against Human (Homo sapiens)
Host Rabbit
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias Dual specificity protein phosphatase CDC14A;3.1.3.16;3.1.3.48;CDC14 cell division cycle 14 homolog A;CDC14A;
Lieferbar
Manufacturer - Category
Primary Antibodies
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
66574 MW
Clonality
Polyclonal
Application Details
Western blotting: 1:500~1:3000
Manufacturer - Gene Name
CDC14A
Gene Full Name
Dual specificity protein phosphatase CDC14A
Background
Dual-specificity phosphatase. Required for centrosome separation and productive cytokinesis during cell division. May dephosphorylate the APC subunit FZR1/CDH1, thereby promoting APC-FZR1 dependent degradation of mitotic cyclins and subsequent exit from mitosis.
Li L., J. Biol. Chem. 272:29403-29406(1997).
Wong A.K.C., Genomics 59:248-251(1999).
Gregory S.G., Nature 441:315-321(2006).
Immunogen
Synthesized peptide derived from Internal of human CC14A.
Contents
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Manufacturer - Research Category
Cell Biology, Cell Cycle, Epigenetics and Nuclear Signaling, Kinases/Phosphatases
Protein Function
Dual-specificity phosphatase. Required for centrosome separation and productive cytokinesis during cell division. Dephosphorylates SIRT2 around early anaphase. May dephosphorylate the APC subunit FZR1/CDH1, thereby promoting APC-FZR1 dependent degradation of mitotic cyclins and subsequent exit from mitosis.
Subcellular Localization
Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle. Centrosomal during interphase, released into the cytoplasm at the onset of mitosis. Subsequently localizes to the midzone of the mitotic spindle.
Short Description
Boster Bio Anti-CC14A CDC14A Antibody (Catalog # A05617). Tested in WB applications. This antibody reacts with Human.
Description
Boster Bio Anti-CC14A CDC14A Antibody (Catalog # A05617). Tested in WB applications. This antibody reacts with Human.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ul
Lieferbar: In stock
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