Anti-Rad51 Rabbit Monoclonal Antibody

Primary Antibodies, Rabbit Monoclonal Antibodies

36966 MW

WB 1:5000-1:10000
IHC 1:100-1:500
ICC/IF 1:100-1:500
IP 1:50
FC 1:100

Runt-related transcription factor 1

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5 mg/ml BSA.

Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Participates in a common DNA damage response pathway associated with the activation of homologous recombination and double-strand break repair. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Underwinds duplex DNA and forms helical nucleoprotein filaments. Part of a PALB2- scaffolded HR complex containing BRCA2 and RAD51C and which is thought to play a role in DNA repair by HR. Plays a role in regulating mitochondrial DNA copy number under conditions of oxidative stress in the presence of RAD51C and XRCC3.