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Anti-TRPM8 Monoclonal Antibody Europäischer Partner

ArtNr BOS-M01002
Hersteller Boster
Menge 100 ul
Kategorie
Typ Antibody Monoclonal
Format Liquid
Applikationen WB, IF, ICC
Clon ADBI-20
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host Rabbit
Isotype IgG
Sensitivity <10pg/ml
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Alias TAR DNA-binding protein 43;TDP-43;TARDBP;TDP43;
Lieferbar
Manufacturer - Category
Rabbit Monoclonal Antibodies
Manufacturer - Isotype
Rabbit IgG
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
45 kDa
Calculated Molecular weight
44740 MW
Clonality
Monoclonal
Application Details
WB 1:500-1:2000
ICC/IF 1:50-1:200
Manufacturer - Gene Name
TRPM8
Gene Full Name
TAR DNA-binding protein 43
Immunogen
A synthesized peptide derived from human TRPM8
Contents
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5 mg/ml BSA.
Purification
Affinity-chromatography
Reconstitution
Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL
Concentration
Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
Manufacturer - Research Category
Cancer, Channels, Metabolism, Neuroscience, Plasma Membrane, Sensory System, Signal Transduction
Protein Name
Glycogen synthase kinase-3 beta (gsk3b)
Protein Function
DNA and RNA-binding protein which regulates transcription and splicing. Involved in the regulation of CFTR splicing. It promotes CFTR exon 9 skipping by binding to the UG repeated motifs in the polymorphic region near the 3'-splice site of this exon. The resulting aberrant splicing is associated with pathological features typical of cystic fibrosis. May also be involved in microRNA biogenesis, apoptosis and cell division. Can repress HIV-1 transcription by binding to the HIV-1 long terminal repeat. Stabilizes the low molecular weight neurofilament (NFL) mRNA through a interaction with the 3' UTR.
Subcellular Localization
Nucleus. In patients with frontotemporal lobar degeneration and amyotrophic lateral sclerosis, it is absent from the nucleus of affected neurons but it is the primary component of cytoplasmic ubiquitin-positive inclusion bodies.
Description
Boster Bio Anti-TRPM8 Monoclonal Antibody catalog # M01002. Tested in WB, ICC/IF applications. This antibody reacts with Human, Mouse.
Tissue Specificity
Ubiquitously expressed. In particular, expression is high in pancreas, placenta, lung, genital tract and spleen.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ul
Lieferbar: In stock
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