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Anti-Podoplanin PDPN Rabbit Monoclonal Antibody

Anti-Podoplanin PDPN Rabbit Monoclonal Antibody

Hersteller	Boster
Kategorie	Food Safety Vitamines Neuroscience Neuroinflammation Antibodies Immunohistochemistry Western Blot Primary Antibodies
Typ	Antibody Monoclonal
Specific against	Human
Clon	AAHB-16
Isotype	IgG
Format	Liquid
Applikationen	WB, IHC
Menge	100 ul
Host	Rabbit
ArtNr	BOS-M01124-2
Targets	PDPN
eClass 6.1	32160702
eClass 9.0	42030590
Lieferbar
Manufacturers Product Category	Primary Antibodies, Rabbit Monoclonal Antibodies
Manufacturers Research Category	Angiogenesis, Cardiovascular, Cell Type Markers, Tags & Cell Markers, Vasculature
Short Description	Boster Bio Anti-Podoplanin PDPN Rabbit Monoclonal Antibody catalog # M01124-2. Tested in WB, IHC applications. This antibody reacts with Human.
Description	Boster Bio Anti-Podoplanin PDPN Rabbit Monoclonal Antibody catalog # M01124-2. Tested in WB, IHC applications. This antibody reacts with Human.
Gene Name	PDPN
Application Details	WB 1:500-1:2000 IHC 1:50-1:200
Clonality	Monoclonal
Concentration	Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
Contents	Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.
Immunogen	A synthesized peptide derived from human Podoplanin
Purification	Affinity-chromatography
Storage	Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Gene Full Name	Podoplanin
Molecular Weight	16698 MW
Protein Function	May be involved in cell migration and/or actin cytoskeleton organization. When expressed in keratinocytes, induces changes in cell morphology with transfected cells showing an elongated shape, numerous membrane protrusions, major reorganization of the actin cytoskeleton, increased motility and decreased cell adhesion. Required for normal lung cell proliferation and alveolus formation at birth. Induces platelet aggregation. Does not have any effect on folic acid or amino acid transport. Does not function as a water channel or as a regulator of aquaporin-type water channels..
Subcellular Localization	Membrane ; Single-pass type I membrane protein. Cell projection, filopodium membrane ; Single-pass type I membrane protein. Cell projection, lamellipodium membrane ; Single-pass type I membrane protein. Cell projection, microvillus membrane ; Single-pass type I membrane protein. Cell projection, ruffle membrane ; Single-pass type I membrane protein. Localized to actin-rich microvilli and plasma membrane projections such as filopodia, lamellipodia and ruffles..
Tissue Specificity	Highly expressed in placenta, lung, skeletal muscle and brain. Weakly expressed in brain, kidney and liver. In placenta, expressed on the apical plasma membrane of endothelium. In lung, expressed in alveolar epithelium. Up-regulated in colorectal tumors and expressed in 25% of early oral squamous cell carcinomas..

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Menge: 100 ul

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Lieferung vsl. bis 16.05.2024

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