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Anti-Podoplanin PDPN Rabbit Monoclonal Antibody

Anti-Podoplanin PDPN Rabbit Monoclonal Antibody

Item no.	BOS-M01124-2
Manufacturer	Boster
Amount	100 ul
Category	Food Safety Vitamines Neuroscience Neuroinflammation Antibodies Immunohistochemistry Western Blot Primary Antibodies
Type	Antibody Monoclonal
Format	Liquid
Applications	WB, IHC
Clone	AAHB-16
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Sensitivity	<10pg/ml
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Podoplanin;Aggrus;Glycoprotein 36;Gp36;PA2.26 antigen;T1-alpha;T1A;PDPN ;GP36 ;PSEC0003, PSEC0025;
Available
Manufacturer - Category	Rabbit Monoclonal Antibodies
Manufacturer - Isotype	Rabbit IgG
Storage Conditions	Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight	80 kDa
Calculated Molecular weight	16698 MW
Clonality	Monoclonal
Application Details	WB 1:500-1:2000 IHC 1:50-1:200
Manufacturer - Gene Name	PDPN
Gene Full Name	Podoplanin
Immunogen	A synthesized peptide derived from human Podoplanin
Contents	Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5 mg/ml BSA.
Purification	Affinity-chromatography
Reconstitution	Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL
Concentration	Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
Manufacturer - Research Category	Angiogenesis, Cardiovascular, Cell Type Markers, Tags & Cell Markers, Vasculature
Protein Name	Glycogen synthase kinase-3 beta (gsk3b)
Protein Function	May be involved in cell migration and/or actin cytoskeleton organization. When expressed in keratinocytes, induces changes in cell morphology with transfected cells showing an elongated shape, numerous membrane protrusions, major reorganization of the actin cytoskeleton, increased motility and decreased cell adhesion. Required for normal lung cell proliferation and alveolus formation at birth. Induces platelet aggregation. Does not have any effect on folic acid or amino acid transport. Does not function as a water channel or as a regulator of aquaporin-type water channels.
Subcellular Localization	Membrane; Single-pass type I membrane protein. Cell projection, filopodium membrane; Single-pass type I membrane protein. Cell projection, lamellipodium membrane; Single-pass type I membrane protein. Cell projection, microvillus membrane; Single-pass type I membrane protein. Cell projection, ruffle membrane; Single-pass type I membrane protein. Localized to actin-rich microvilli and plasma membrane projections such as filopodia, lamellipodia and ruffles.
Description	Boster Bio Anti-Podoplanin PDPN Rabbit Monoclonal Antibody catalog # M01124-2. Tested in WB, IHC applications. This antibody reacts with Human.
Tissue Specificity	Highly expressed in placenta, lung, skeletal muscle and brain. Weakly expressed in brain, kidney and liver. In placenta, expressed on the apical plasma membrane of endothelium. In lung, expressed in alveolar epithelium. Up-regulated in colorectal tumors and expressed in 25% of early oral squamous cell carcinomas.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

BOS-M01124-2-datasheet.pdf

BOS-M01124-2-safety-datasheet.pdf