Anti-Podoplanin (PDPN) (Lymphatic Endothelial & Mesothelial Marker) Monoclonal Antibody

Primary Antibodies, Monoclonal Antibodies

Boster Bio Anti-Podoplanin (PDPN) (Lymphatic Endothelial & Mesothelial Marker) Monoclonal Antibody (Catalog # M01124). Tested in ELISA, IF, IHC applications. This antibody reacts with Human.

This monoclonal antibody recognizes a muco-protein of 38-43kDa, which is identified as Podoplanin (PDPN). It localizes in stromal cells of peripheral lymphoid tissue and thymic epithelial cells. As a regulator of the lymphatic endothelium, podoplanin probably plays a role in maintaining the unique shape of podocytes. It is selectively expressed in lymphatic endotheliumas well as lymphoangiomas, Kaposi sarcomas, and in a subset of angiosarcomas with probable lymphatic differentiation. Recent studies have also shown podoplanin to be a highly sensitive and relatively specific marker for epithelioid mesothelioma. Therefore, it can be used in a panel to distinguish mesotheliomas or mesothelial cells from pulmonary carcinomas.

Monoclonal

Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Recombinant human Podoplanin (PDPN) protein fragment (around aa 24-126) (exact sequence is proprietary)

Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

16698 MW

Cell Surface and Cytoplasmic