Anti-LC3B MAP1LC3B Rabbit Monoclonal Antibody

Rabbit Monoclonal Antibodies

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

14688 MW

WB 1:500-1:2000
ICC/IF 1:50-1:200
IP 1:50

Microtubule-associated proteins 1A/1B light chain 3B

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5 mg/ml BSA.

Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Developmental Biology, Endocrine System, Epigenetics and Nuclear Signaling, Neuroscience, Nuclear Receptors, Nuclear Signaling Pathways, Reproduction

Ubiquitin-like modifier involved in formation of autophagosomal vacuoles (autophagosomes). Plays a role in mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Whereas LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation. Promotes primary ciliogenesis by removing OFD1 from centriolar satellites via the autophagic pathway.

Boster Bio Anti-LC3B MAP1LC3B Rabbit Monoclonal Antibody catalog # M01524. Tested in WB, ICC/IF, IP applications. This antibody reacts with Human, Mouse, Rat.