Anti-SFRP1 Rabbit Monoclonal Antibody

Rabbit Monoclonal Antibodies

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

35386 MW

WB 1:500-1:2000
IHC 1:50-1:200
ICC/IF 1:50-1:200

Secreted frizzled-related protein 1

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5 mg/ml BSA.

Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Axonal Guidance Proteins, Cell Biology, Developmental Biology, Growth and Development, Neurology Process, Neuroscience, Organogenesis, Proteasome, Proteasome / Ubiquitin, Proteolysis/Ubiquitin, Secreted, Signaling Pathways, Stem Cells

Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP1 decreases intracellular beta-catenin levels (By similarity). Has antiproliferative effects on vascular cells, in vitro and in vivo, and can induce, in vivo, an angiogenic response. In vascular cell cycle, delays the G1 phase and entry into the S phase (By similarity). In kidney development, inhibits tubule formation and bud growth in metanephroi (By similarity). Inhibits WNT1/WNT4-mediated TCF-dependent transcription.

Boster Bio Anti-SFRP1 Rabbit Monoclonal Antibody catalog # M01968. Tested in WB, IHC, ICC/IF applications. This antibody reacts with Human.