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Anti-EBP50 SLC9A3R1 Rabbit Monoclonal Antibody Europäischer Partner

ArtNr BOS-M02427
Hersteller Boster
Menge 100 ul
Kategorie
Typ Antibody Monoclonal
Format Liquid
Applikationen WB, IHC
Clon IIH-19
Specific against Human (Homo sapiens), Rat (Rattus norvegicus)
Host Rabbit
Isotype IgG
Sensitivity <20pg/ml
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Alias Na (+)/H (+) exchange regulatory cofactor NHE-RF1;NHERF-1;Ezrin-radixin-moesin-binding phosphoprotein 50;EBP50;Regulatory cofactor of Na (+)/H (+) exchanger;Sodium-hydrogen exchanger regulatory factor 1;Solute carrier family 9 isoform A3 regulatory factor 1;SLC9A3R1;NHERF, NHERF1;
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Manufacturer - Category
Rabbit Monoclonal Antibodies
Manufacturer - Isotype
Rabbit IgG
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
80 kDa
Calculated Molecular weight
38868 MW
Clonality
Monoclonal
Application Details
WB 1:500-1:2000
IHC 1:50-1:200
Manufacturer - Gene Name
SLC9A3R1
Gene Full Name
Na(+)/H(+) exchange regulatory cofactor NHE-RF1
Immunogen
A synthesized peptide derived from human EBP50
Contents
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5 mg/ml BSA.
Purification
Affinity-chromatography
Reconstitution
Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL
Concentration
Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
Manufacturer - Research Category
Actin Binding Proteins, Actin, etc., Adapters, Cancer, Cell Type Markers, Cytoskeleton, Cytoskeleton/ECM, Extracellular Matrix, Invasion/Microenvironment, Microfilaments, Signal Transduction, Tags & Cell Markers, Transmembrane
Protein Name
T-cell surface glycoprotein CD3 zeta chain
Protein Function
Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression. Necessary for recycling of internalized ADRB2. Was first known to play a role in the regulation of the activity and subcellular location of SLC9A3. Necessary for cAMP-mediated phosphorylation and inhibition of SLC9A3. May enhance Wnt signaling. May participate in HTR4 targeting to microvilli (By similarity). Involved in the regulation of phosphate reabsorption in the renal proximal tubules. Involved in sperm capacitation. May participate in the regulation of the chloride and bicarbonate homeostasis in spermatozoa.
Subcellular Localization
Cytoplasm. Apical cell membrane. Endomembrane system; Peripheral membrane protein. Cell projection, filopodium. Cell projection, ruffle. Cell projection, microvillus. Translocates from the cytoplasm to the apical cell membrane in a PODXL-dependent manner. Colocalizes with CFTR at the midpiece of sperm tail (By similarity). Colocalizes with actin in microvilli-rich apical regions of the syncytiotrophoblast. Found in microvilli, ruffling membrane and filopodia of HeLa cells. Present in lipid rafts of T- cells.
Description
Boster Bio Anti-EBP50 SLC9A3R1 Rabbit Monoclonal Antibody catalog # M02427. Tested in WB, IHC applications. This antibody reacts with Human, Rat.
Tissue Specificity
Detected in liver, kidney, pancreas, prostate, spleen, small intestine and placenta, in particular in the syncytiotrophoblast.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ul
Lieferbar: In stock
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