Hersteller |
Boster
|
Kategorie |
|
Typ |
Antibody Monoclonal |
Specific against |
Human, Mouse, Rat |
Clon |
AAFH-6 |
Isotype |
IgG |
Format |
Liquid |
Applikationen |
WB, IF, ICC |
Menge |
100 ul |
Host |
Rabbit |
ArtNr |
BOS-M04492 |
eClass 6.1 |
32160702 |
eClass 9.0 |
42030590 |
Lieferbar |
|
Manufacturers Product Category |
Primary Antibodies, Rabbit Monoclonal Antibodies |
Manufacturers Research Category |
Immunology |
Short Description |
Boster Bio Anti-FKBP12 Rabbit Monoclonal Antibody catalog # M04492. Tested in WB, ICC/IF applications. This antibody reacts with Human, Mouse, Rat. |
Description |
Boster Bio Anti-FKBP12 Rabbit Monoclonal Antibody catalog # M04492. Tested in WB, ICC/IF applications. This antibody reacts with Human, Mouse, Rat. |
Gene Name |
FKBP1A |
Application Details |
WB 1:1000-1:5000 ICC/IF 1:50-1:200 |
Clonality |
Monoclonal |
Concentration |
Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure. |
Contents |
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA. |
Immunogen |
A synthesized peptide derived from human FKBP12 |
Purification |
Affinity-chromatography |
Storage |
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles. |
Gene Full Name |
Peptidyl-prolyl cis-trans isomerase FKBP1A |
Molecular Weight |
11951 MW |
Protein Function |
Keeps in an inactive conformation TGFBR1, the TGF-beta type I serine/threonine kinase receptor, preventing TGF-beta receptor activation in absence of ligand. Recruites SMAD7 to ACVR1B which prevents the association of SMAD2 and SMAD3 with the activin receptor complex, thereby blocking the activin signal. May modulate the RYR1 calcium channel activity. PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.. |
Subcellular Localization |
Cytoplasm. |
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