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Anti-FKBP12 Rabbit Monoclonal Antibody

Anti-FKBP12 Rabbit Monoclonal Antibody

Manufacturer	Boster
Category	Neuroscience Neural Lineage Markers Antibodies Immunofluorescence Immunocytochemistry Primary Antibodies Neurodegeneration Markers;Research Area Protein Aggregation, Clearance & Misfolding
Type	Antibody Monoclonal
Specific against	Human, Mouse, Rat
Clone	AAFH-6
Isotype	IgG
Format	Liquid
Applications	WB, IF, ICC
Amount	100 ul
Host	Rabbit
Item no.	BOS-M04492
eClass 6.1	32160702
eClass 9.0	42030590
Available
Manufacturers Product Category	Primary Antibodies, Rabbit Monoclonal Antibodies
Manufacturers Research Category	Immunology
Short Description	Boster Bio Anti-FKBP12 Rabbit Monoclonal Antibody catalog # M04492. Tested in WB, ICC/IF applications. This antibody reacts with Human, Mouse, Rat.
Description	Boster Bio Anti-FKBP12 Rabbit Monoclonal Antibody catalog # M04492. Tested in WB, ICC/IF applications. This antibody reacts with Human, Mouse, Rat.
Gene Name	FKBP1A
Application Details	WB 1:1000-1:5000 ICC/IF 1:50-1:200
Clonality	Monoclonal
Concentration	Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
Contents	Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.
Immunogen	A synthesized peptide derived from human FKBP12
Purification	Affinity-chromatography
Storage	Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Gene Full Name	Peptidyl-prolyl cis-trans isomerase FKBP1A
Molecular Weight	11951 MW
Protein Function	Keeps in an inactive conformation TGFBR1, the TGF-beta type I serine/threonine kinase receptor, preventing TGF-beta receptor activation in absence of ligand. Recruites SMAD7 to ACVR1B which prevents the association of SMAD2 and SMAD3 with the activin receptor complex, thereby blocking the activin signal. May modulate the RYR1 calcium channel activity. PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides..
Subcellular Localization	Cytoplasm.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ul

available

Delivery expected until 6/13/2024