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Anti-Cytokeratin, pan (Epithelial Marker) Antibody Europäischer Partner

ArtNr BOS-M14209-3
Hersteller Boster
Menge 100 ug
Kategorie
Typ Antibody
Format Liquid
Applikationen WB, FC, IF
Clon N/A
Specific against Human (Homo sapiens)
Host Rabbit
Isotype IgG
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias Keratin, type II cytoskeletal 1b;Cytokeratin-1B;CK-1B;Keratin-77;K77;Type-II keratin Kb39;KRT77;KRT1B;
Lieferbar
Manufacturer - Category
Primary Antibodies
Manufacturer - Isotype
IgG, kappa
Storage Conditions
Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Observed Molecular Weight
61901 MW
Clonality
Polyclonal
Application Details
Flow Cytometry (0.5-1ug/million cells)
Immunofluorescence (1-2ug/ml)
Western Blotting (0.5-1ug/ml for 2 hours at RT)
Immunohistology (Formalin-fixed) (0.25-0.5ug/ml for 30 min at RT) (Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)
Optimal dilution for a specific application should be determined.
Manufacturer - Gene Name
Multiple
Gene Full Name
Keratin, type II cytoskeletal 1b
Background
Twenty human keratins are resolved with two-dimensional gel electrophoresis into acidic (pI 6.0) subfamilies. This antibody cocktail recognizes acidic (Type I or LMW) and basic (Type II or HMW) cytokeratins, which 67kDa (CK1); 64kDa (CK3); 59kDa (CK4); 58kDa (CK5); 56kDa (CK6); 52kDa (CK8); 56.5kDa (CK10); 50kDa (CK14); 50kDa (CK15); 48kDa (CK16); 40kDa (CK19). Many studies have shown the usefulness of keratins as markers in cancer research and tumor diagnosis. It is a broad spectrum anti pan-cytokeratin antibody, which differentiates epithelial tumors from non-epithelial tumors e.g. squamous vs. adenocarcinoma of the lung, liver carcinoma, breast cancer, and esophageal cancer. It may be useful to characterize the source of various neoplasms and to study the distribution of cytokeratin containing cells in epithelia during normal development and during the development of epithelial neoplasms. This antibody stains cytokeratins present in normal and abnormal human tissues and has high sensitivity in the recognition of epithelial cells and carcinomas.
Immunogen
Recombinant full-length human KRT76 and KRT77 proteins
Contents
Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Purification
200ug/ml of antibody purified by Protein A.
Concentration
Purified antibody with BSA and azide at 200ug/ml
Manufacturer - Research Category
Class I, Cytoskeleton, Cytoskeleton/ECM, Intermediate Filaments, Keratin, Signal Transduction
Subcellular Localization
Cytoplasmic
Short Description
Boster Bio Anti-Cytokeratin, pan (Epithelial Marker) Antibody (Catalog # M14209-3). Tested in Flow Cytometry, IF, WB applications. This antibody reacts with Human.
Description
Boster Bio Anti-Cytokeratin, pan (Epithelial Marker) Antibody (Catalog # M14209-3). Tested in Flow Cytometry, IF, WB applications. This antibody reacts with Human.
Tissue Specificity
Expressed exclusively in skin.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ug
Lieferbar: In stock
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