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Anti-Phospho RapGEF1 (Tyr504) Antibody

Anti-Phospho RapGEF1 (Tyr504) Antibody

ArtNr	BOS-P06527
Hersteller	Boster
Menge	100 ul
Kategorie	Neuroscience Molecular Targets for Neuroscience Targets for Rodent Neurosciences Neural Signaling Antibodies Western Blot Primary Antibodies
Typ	Antibody
Format	Liquid
Applikationen	WB, IF, ELISA, IHC-P
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Sensitivity	>5000 cells
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	RAPGEF1;GRF2;Rap guanine nucleotide exchange factor 1;CRK SH3-binding GNRP;Guanine nucleotide-releasing factor 2;Protein C3G
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Manufacturer - Category	Primary Antibodies
Manufacturer - Isotype	Rabbit IgG
Storage Conditions	Store at -20°C for one year. For short-term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight	120548 MW
Clonality	Polyclonal
Application Details	Western Blot, 1:500 - 1:2000 ELISA, 1:10000 Not yet tested in other applications.
Manufacturer - Gene Name	RAPGEF1
Gene Full Name	Rap guanine nucleotide exchange factor 1
Immunogen	A peptide derived from human RapGEF1 around the phosphorylation site of Tyr504. Immunogen sequence location: 470-519
Contents	PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification	The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.
Concentration	0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
Manufacturer - Research Category	G Protein Signaling, Ras Family, Regulators, Signal Transduction, Signaling Pathway, Small G Proteins
Protein Function	Guanine nucleotide-releasing protein that binds to SH3 domain of CRK and GRB2/ASH. Transduces signals from CRK to activate RAS. Plays a role in the establishment of basal endothelial barrier function. Plays a role in nerve growth factor (NGF)-induced sustained activation of Rap1 and neurite outgrowth.
Subcellular Localization	Early endosome.
Short Description	Boster Bio Anti-Phospho RapGEF1 (Tyr504) Antibody (Catalog# P06527). Tested in WB, IHC-P, IF (paraffin), ELISA applications. This antibody reacts with Human, Rat, Mouse.
Description	Boster Bio Anti-Phospho RapGEF1 (Tyr504) Antibody (Catalog# P06527). Tested in WB, IHC-P, IF (paraffin), ELISA applications. This antibody reacts with Human, Rat, Mouse.
Tissue Specificity	Ubiquitously expressed in adult and fetus. Expression is high in adult skeletal muscle and placenta and in fetal brain and heart. Low levels of expression in adult and fetal liver.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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BOS-P06527-datasheet.pdf

BOS-P06527-safety-datasheet.pdf