Connexin 43 (Phospho-Ser367) Colorimetric Cell-Based ELISA Kit

Store at 4°C for up to 6 months.

GJA1

Gap junction protein that acts as a regulator of bladder capacity. A gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. May play a critical role in the physiology of hearing by participating in the recycling of potassium to the cochlear endolymph. Negative regulator of bladder functional capacity: acts by enhancing intercellular electrical and chemical transmission, thus sensitizing bladder muscles to cholinergic neural stimuli and causing them to contract (By similarity). May play a role in cell growth inhibition through the regulation of NOV expression and localization. Plays an essential role in gap junction communication in the ventricles (By similarity).

The Connexin 43 (Phospho-Ser367) Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor Connexin 43 (Phospho-Ser367) protein expression profile in cells. The kit can be used for measuring the relative amounts of Connexin 43 (Phospho-Ser367) in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on Connexin 43 (Phospho-Ser367).

Expressed in the heart and fetal cochlea.