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VTCN1 Human, V-Set Domain Containing T Cell Activation Inhibitor 1 Human Recombinant Protein, Sf9

VTCN1 Human, V-Set Domain Containing T Cell Activation Inhibitor 1 Human Recombinant Protein, Sf9

ArtNr	BOS-PROTQ7Z7D3-1
Hersteller	Boster
Menge	5 ug
Kategorie	Oncology By Cell Type Carcinoma Peptides & Proteins Recombinant Proteins
Typ	Proteins Recombinant
Format	Liquid
Specific against	other
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	V-set domain-containing T-cell activation inhibitor 1;B7 homolog 4;B7-H4;B7h.5;Immune costimulatory protein B7-H4;Protein B7S1;T-cell costimulatory molecule B7x;VTCN1
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Storage Conditions	Store in -20°C for long term storage. After reconstitution, store in 4°C for short term usage within a few days. Avoid freeze-thaw cycles.
Manufacturer - Format	Solution
Manufacturer - Gene Name	VTCN1
Contents	VTCN1 protein solution (0.25 mg/ml) contains Phosphate Buffered Saline (pH 7.4) and 10% glycerol.
Purification	Greater than 90.0% as determined by SDS-PAGE.
Protein Function	Negatively regulates T-cell-mediated immune response by inhibiting T-cell activation, proliferation, cytokine production and development of cytotoxicity. When expressed on the cell surface of tumor macrophages, plays an important role, together with regulatory T-cells (Treg), in the suppression of tumor- associated antigen-specific T-cell immunity. Involved in promoting epithelial cell transformation.
Tissue Specificity	Overexpressed in breast, ovarian, endometrial, renal cell (RCC) and non-small-cell lung cancers (NSCLC). Expressed on activated T- and B-cells, monocytes and dendritic cells, but not expressed in most normal tissues (at protein level). Widely expressed, including in kidney, liver, lung, ovary, placenta, spleen and testis.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Arbeitsanleitung (Data Sheet) anfordern

BOS-PROTQ7Z7D3-1-datasheet.pdf

BOS-PROTQ7Z7D3-1-safety-datasheet.pdf