PKN3 Polyclonal Antibody

Catalytic activity:ATP + a protein = ADP + a phosphoprotein., The C1 domain does not bind the diacylglycerol (DAG)., enzyme regulation:Two specific sites, Thr-718 (activation loop of the kinase domain) and Thr-860 (turn motif), need to be phosphorylated for its full activation., Contributes to invasiveness in malignant prostate cancer., PTM:Autophosphorylated., Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily., Contains 1 AGC-kinase C-terminal domain., Contains 1 protein kinase domain., Contains 3 REM (Hr1) repeats., subcellular location:Nuclear and perinuclear Golgi region., tissue specificity:Expressed in prostate tumors and various cancer cell lines. Not expressed in adult tissues.,

1 mg/ml

-20°C for 1 year