CD105 Antibody [MJ7/18]

CD105 Antibody [MJ7/18] for use in flow cytometry, immunohistochemistry, western blotting, immunoprecipitation, and separation assays.

Store vial at 2-8°C

CD105, also known as endoglin, is a disulfide-linked type II transmembrane homodimer that is predominantly expressed on vascular endothelial cells. It is also found on pre-erythroblasts, macrophages, and lymphoid and myeloid leukemic cells. Both mouse and human CD105 exhibit >70% sequence homology in their cytoplasmic domains with type III transforming growth factor beta (TGFbeta) receptor. CD105 has been shown to be one of several receptors for the various isoforms of TGFbeta which in turn is one of a family of proteins involved in regulation of cell differentiation, migration of cells, and control of the immune response.

Supplied in borate buffered saline, pH 8.2; No preservatives or amine-containing buffer salts added

Monoclonal

Mus musculus