Vergleich

Anti-Amyloid Beta Peptide 1-40 (Ab1-40)

ArtNr ARP-20-3314
Hersteller American Research Products
Menge 50 ug
Kategorie
Typ Antibody Polyclonal
Applikationen WB, IHC, ICC, ELISA
Specific against other
Host Rabbit
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias Ab1-40 Polyclona Antibody
Lieferbar
Description
  • Amyloid beta-protein (Ab) is a peptide composed of 40 to 42 (43) amino acids, and is said to be cleaved out of the precursor protein APP (a protein composed of 695, 751, or 770 amino acids) by the action of b- or gamma-secretase.
  • Abeta1-40 stimulated microglial cells and macrophages primed by interferon-gamma in a dose-dependent manner. Co-administration of Abeta1-40 with LPS or Pam3Cys led to an additive release of nitric oxide (NO) and tumour necrosis factor alpha (TNF-alpha). This may be one reason for the clinical deterioration frequently observed in patients with Alzheimer's disease during infections. In contrast, co-application of Abeta1-40 with CpG led to a substantial decrease of NO and TNF-alpha release compared with stimulation with CpG alone. Abeta1-40 and CpG did not co-localize within the same subcellular compartment, making a direct physicochemical interaction as the cause of the observed antagonism very unlikely.
Form
Liquid
Working Dilution
Western blotting: 1:100-400, Immunocytochemistry in formalin fixed cells: 1:100-500, Immunohistochemistry in formalin fixed frozen section: 1:100-500, Immunohistochemistry in paraffin section: 1:50-417
Storage
2-8C for immediate use, or at -20C (aliquot)
Synonyms
Ab1-40 Polyclona Antibody
Concentration
0.2mg/ml
Antigen Recognized in Species
Rat
Purification
Affinity chromatography

Hinweis: Die dargestellten Informationen und Dokumente (Bedienungsanleitung, Produktdatenblatt, Sicherheitsdatenblatt und Analysezertifikat) entsprechen unserem letzten Update und sollten lediglich der Orientierung dienen. Wir übernehmen keine Garantie für die Aktualität. Für spezifische Anforderungen bitten wir Sie, uns eine Anfrage zu stellen.

Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 50 ug
Lieferbar: In stock
lieferbar

Vergleichen

Auf den Wunschzettel

Angebot anfordern

Lieferzeit anfragen

Technische Frage stellen

Bulk-Anfrage stellen

Fragen zum Produkt?
 
Schließen