Anti-Cluster Of Differentiation 3d (CD3d)

In immunology, the CD3 T-Cell Co-Receptor (CD stands for cluster of differentiation) is a protein complex and is composed of four distinct chains. In mammals, the complex contains a CD3gamma chain, a CD3 chain, and two CD3 chains. CD3d is part of the T-cell receptor/CD3 complex (TCR/CD3 complex) and is involved in T-cell development and signal transduction. The encoded membrane protein represents the delta subunit of the CD3 complex, and along with four other CD3 subunits, binds either TCR alpha/beta or TCR gamma/delta to form the TCR/CD3 complex on the surface of T-cells. Defects in this gene are a cause of severe combined immunodeficiency autosomal recessive T-cell-negative/B-cell-positive/NK-cell-positive (SCIDBNK). Two transcript variants encoding different isoforms have been found for this gene.

Western blotting: 1:100-400, Immunocytochemistry in formalin fixed cells: 1:100-500, Immunohistochemistry in formalin fixed frozen section: 1:100-500, Immunohistochemistry in paraffin section: 1:50-417

CD3-DELTA, T3D, T-Dell Surface Glycoprotein CD3 Delta Chain

Pig