EGFR Polyclonal Antibody

EGFR

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

175kDa

EGFR, also named as ERBB1, is a cell-surface receptor for members of the epidermal growth factor family (EGF-family) of extracellular protein ligands. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. The gene resides on chromosome 7p12, encoding a 170 kDa membrane-associated glycoprotein. Recent studies have shown EGFR plays a critical role in cancer development and progression, including cell proliferation, apoptosis, angiogenesis, and metastatic spread. Mutations in this gene are associated with lung cancer.

PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4

WB 1:500-1:2000

Polyclonal

Polyclonal Antibodies