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PUS1 Antibody (C-term)

ArtNr ABC-AP12835b-ev
Hersteller Abcepta
Menge 80 ul
Kategorie
Typ Antibody Primary
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Applikationen WB, IHC-P
Specific against other
Host Rabbit
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Similar products PUS1, mitochondrial, tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I
Lieferbar
Primary Accession
Q9Y606
Antigen Type
Synthetic Peptide
Application
IHC-P, WB
Bio Background
This gene encodes a pseudouridine synthase that converts
uridine to pseudouridine once it has been incorporated into an RNA
molecule. The encoded enzyme may play an essential role in tRNA
function and in stabilizing the secondary and tertiary structure of
many RNAs. A mutation in this gene has been linked to mitochondrial
myopathy and sideroblastic anemia. Alternate splicing results in
multiple transcript variants.
Bio References
Bergmann, A.K., et al. Pediatr Blood Cancer 54(2):273-278(2010)
Sibert, B.S., et al. RNA 14(9):1895-1906(2008)
Rikova, K., et al. Cell 131(6):1190-1203(2007)
Sugiyama, N., et al. Mol. Cell Proteomics 6(6):1103-1109(2007)
Fernandez-Vizarra, E., et al. J. Med. Genet. 44(3):173-180(2007)
Clonality
Polyclonal
Clone/Animal Names
RB32559
Gene ID
80324
Gene Name
PUS1
Subtitle
Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity
H
Legend image 1
PUS1 Antibody (C-term) (Cat. #AP12835b) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the PUS1 antibody detected the PUS1 protein (arrow).
Type image 1
WB
Dilution image 1
1:1000
Legend image 2
PUS1 Antibody (C-term) (Cat. #AP12835b)immunohistochemistry analysis in formalin fixed and paraffin embedded human skeletal muscle followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of PUS1 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
Type image 2
IHC-P
Dilution image 2
1:10~50
Other Accession
NP_001002019.1; NP_079491.2
Isotype
Rabbit Ig
Calculated MW
47470
Antigen Region
322-350
Antigen Source
HUMAN
Target/Specificity
This PUS1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 322-350 amino acids from the C-terminal region of human PUS1.
NCBI Accession
NP_001002019.1; NP_001002020.1; NP_079491.2

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 80 ul
Lieferbar: In stock
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