Anti-MCM6 Antibody

ArtNr	ABC-ABO11077
Hersteller	Abcepta
Menge	100 ug
Kategorie	Antibodies Primary Antibodies
Typ	Antibody Primary
Format	Lyophilized
Applikationen	WB, ICC, IHC-P, IHC-F
Specific against	other
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	MCM6, DNA replication licensing factor MCM6, p105MCM, 3.6.4.12
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Primary Accession	Q14566
Application	WB, IHC-P, IHC-F, ICC
Clonality	Polyclonal
Gene ID	4175
Reactivity	H, M, Rat
Legend image 1	Anti-MCM6 antibody, ABO11077, Western blottingLane 1: U87 Cell LysateLane 2: COLO320 Cell LysateLane 3: HELA Cell LysateLane 4: MCF-7 Cell LysateLane 5: JURKAT Cell Lysate
Type image 1	WB
Dilution image 1	0.1-0.5 µg/ml
Legend image 2	Anti-MCM6 antibody, ABO11077, IHC(P)IHC(P): Human Intestinal Cancer Tissue
Type image 2	IHC
Dilution image 2	0.5-1 µg/ml
Legend image 3	Anti-MCM6 antibody, ABO11077, IHC(P)IHC(P): Rat Brain Tissue
Type image 3	IHC
Legend image 4	Anti-MCM6 antibody, ABO11077, ICCICC: HELA Cell
Type image 4	ICC
Legend image 5	Anti-MCM6 antibody, ABO11077, IHC(F)IHC(F): Human Placenta Tissue
Type image 5	IHC
Calculated MW	92889
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Description	Rabbit IgG polyclonal antibody for DNA replication licensing factor MCM6(MCM6) detection. Tested with WB, IHC-P, IHC-F, ICC in Human; Mouse; Rat.
Protein Function	Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity. .
Subcellular Localization	Nucleus. Binds to chromatin during G1 and detach from it during S phase.
Protein Name	DNA replication licensing factor MCM6
Contents	Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
Immunogen	A synthetic peptide corresponding to a sequence in the middle region of human MCM6(589-605aa ESEDFIVEQYKHLRQRD), different from the related rat and mouse sequences by one amino acid.
Purification	Immunogen affinity purified.
Cross Reactivity	No cross reactivity with other proteins
Storage	At -20?C for one year. After r?Constitution, at 4?C for one month. It?Can also be aliquotted and stored frozen at -20?C for a longer time.Avoid repeated freezing and thawing.
Concentration (mg/ml)	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Sequence Similarities	Belongs to the MCM family.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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Menge: 100 ug

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Lieferung vsl. bis 02.10.2025

Express-Lieferung: 20 Tage sparen

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