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Anti-PITRM1 Antibody Picoband®

Anti-PITRM1 Antibody Picoband®

ArtNr	BOS-A08969-1
Hersteller	Boster
Menge	100 ug/vial
Kategorie	Antibodies Primary Antibodies
Typ	Antibody
Format	Lyophilized
Applikationen	WB, FC, IF, ICC, ELISA
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Citations	1. Falkevall, A., Alikhani, N., Bhushan, S., Pavlov, P. F., Busch, K., Johnson, K. A., Eneqvist, T., Tjernberg, L., Ankarcrona, M., Glaser, E. Degradation of the amyloid beta-protein by the novel mitochondrial peptidasome, PreP. J. Biol. Chem. 281: 29096-29104, 2006. 2. Mzhavia, N., Berman, Y. L., Qian, Y., Yan, L., Devi, L. A. Cloning, expression, and characterization of human metalloprotease 1: a novel member of the pitrilysin family of metalloendoproteases. DNA Cell Biol. 18: 369-380, 1999. 3. Teixeira, P. F., Pinho, C. M., Branca, R. M., Lehtio, J., Levine, R. L., Glaser, E. In vitro oxidative inactivation of human presequence protease (hPreP). Free Radic. Biol. Med. 53: 2188-2195, 2012.
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Immunoglobulin lambda-like polypeptide 1; CD179 antigen-like family member B; Ig lambda-5; Immunoglobulin omega polypeptide; Immunoglobulin-related protein 14.1; CD179b; IGLL1; IGL1
Lieferbar
Manufacturer - Category	Primary Antibodies
Manufacturer - Isotype	Rabbit IgG
Storage Conditions	At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
Observed Molecular Weight	117 kDa
Clonality	Polyclonal
Application Details	Western blot, 0.25-0.5 ?g/ml, Human, Mouse, Rat Immunocytochemistry/Immunofluorescence, 5 ?g/ml, Human Flow Cytometry (Fixed), 1-3 ?g/1x10⁶ cells, Human ELISA, 0.1-0.5 ?g/ml, -
Manufacturer - Gene Name	PITRM1
Gene Full Name	immunoglobulin lambda like polypeptide 1
Background	Pitrilysin metallopeptidase 1 also known as presequence protease, mitochondrial (PreP) and metalloprotease 1 (MTP-1) is an enzyme that in humans is encoded by the PITRM1 gene. The protein encoded by this gene is an ATP-dependent metalloprotease that degrades post-cleavage mitochondrial transit peptides. The encoded protein binds zinc and can also degrade amyloid beta A4 protein, suggesting a possible role in Alzheimer's disease.
Immunogen	E.coli-derived human PITRM1 recombinant protein (Position: A33-K1037).
Contents	Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
Purification	Immunogen affinity purified.
Reconstitution	Adding 0.2 ml of distilled water will yield a concentration of 500 ?g/ml.
Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ?g/ml.
Manufacturer - Research Category	Adaptive Immunity, B Cells, Immunoglobulins, Immunology
Protein Function	Critical for B-cell development.
Subcellular Localization	Secreted.
Description	Boster Bio Anti-PITRM1 Antibody Picoband® catalog # A08969-1. Tested in ELISA, Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Tissue Specificity	Expressed only in pre-B-cells and a special B-cell line (which is surface Ig negative).

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BOS-A08969-1-datasheet.pdf

BOS-A08969-1-safety-datasheet.pdf