Rabbit anti-human PTPRC polyclonal antibody

protein tyrosine phosphatase, receptor type, C

Synthetic peptide of human PTPRC

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitosis, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus is classified as a receptor type PTP. This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling.

-20C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Antigen affinity purification