Dynasore

ArtNr	HY-15304-10mM
Hersteller	MedChem Express
CAS-Nr.	304448-55-3
Menge	10 mM/1 mL
Quantity options	10 mM/1 mL 10 mg 50 mg 5 mg
Kategorie	Inhibitors & Compound Libraries Small Molecules
Typ	Inhibitors
Specific against	other
Purity	99.66
Citations	[1]Macia E, et al. Dynasore, a cell-permeable inhibitor of dynamin. Dev Cell. 2006 Jun;10(6):839-50.\|[2]Mues MB, et al. Dynasore disrupts trafficking of herpes simplex virus proteins. J Virol. 2015 Jul;89(13):6673-84.\|[3]Gao D, et al. Dynasore protects mitochondria and improves cardiac lusitropy in Langendorff perfused mouse heart. PLoS One. 2013 Apr 15;8(4):e60967.\|[4]Li G, et al. Dynasore Improves Motor Function Recovery via Inhibition of Neuronal Apoptosis and Astrocytic Proliferation after Spinal Cord Injury in Rats. Mol Neurobiol. 2016 Nov 7.\|[5]Liang Ma, et al. Discovery of the migrasome, an organelle mediating release of cytoplasmic contents during cell migration. Cell Res. 2015 Jan;25(1):24-38. AAPS PharmSciTech. 2023 Feb 15;24(2):69.\|Adv Funct Mater. 2023 Jan 15.\|Adv Funct Mater. 2024 May 1.\|Adv Healthc Mater. 2024 Jul 16:e2401460.\|Adv Mater. 2022 Jul 28;e2204287.\|Adv Mater. 2025 Jan 10:e2415030.\|Adv Sci (Weinh). 2022 Dec 11;e2204871.\|Anal Chem. 2020 Jan 21;92(2):2103-2111.\|Antioxidants (Basel). 2022, 11(12), 2307.\|Arab J Chem. 2020, 13 (1): 2558-2567.\|Biol Res. 2023 Mar 11;56(1):10.\|Biomaterials. 2022 May;284:121529.\|Cancer Immunol Res. 2022 May 17;canimm.0652.2021.\|Cell Commun Signal. 2020 Nov 4;18(1):176.\|Cell Death Differ. 2024 Aug 8.\|Cell Rep. 2022 Jun 14;39(11):110943.\|Comput Struct Biotec. 2021;19:1933-1943.\|Drug Deliv. 2018 Nov;25(1):1066-1079. \|EBioMedicine. 2022 Jul 28;82:104181.\|Elife. 2022 Jun 28;11:e78044.\|Environ Sci Technol. 2023 May 30.\|Eur J Cell Biol. 2019 Jan;98(1):36-50.\|Eur J Pharmacol. 2021 May 25;174203.\|FEBS J. 2024 Sep 15.\|Food Chem. 2024 Sep 8;463(Pt 1):141196.\|Front Cell Dev Biol. 2021 Jul 7;9:687322.\|Int J Biol Macromol. 2022 Jun 16;S0141-8130(22)01308-3.\|Int J Biol Sci. 2024 Sep 3;20(12):4713-4730.\|Int J Pharm. 2024 Apr 25:655:124072.\|J Am Chem Soc. 2018 Dec 12;140(49):17234-17240.\|J Extracell Vesicles. 2021 Jul;10(9):e12117.\|J Hazard Mater. 2021 Sep 5;417:126092.\|J Virol. 2021 Sep 29;JVI0134521.\|Mov Disord. 2023 Oct 5.\|Nano Lett. 2019 Nov 13;19(11):8010-8020. \|Nat Commun. 2021 Jun 9;12(1):3481.\|Nat Nanotechnol. 2020 Dec;15(12):1043-1052.\|Neurotox Res. 2019 Jul;36(1):108-116.\|Oncogene. 2018 Jan 4;37(1):116-127. \|PLoS Pathog. 2021 Jul 21;17(7):e1009752.\|Redox Biol. 2022 Apr;50:102257.\|Redox Biol. 2025 Mar 4:82:103581.\|Research Square Preprint. 2021 Aug.\|Research Square Preprint. 2023 Apr 19.\|Research Square Preprint. 2023 Aug 7.\|Research Square Print. 2022 May.\|Sci Bull. 2020 Jul.\|Sci China Life Sci. 2021 May 27;1-21.\|Sci Rep. 2023 May 25;13(1):8479.\|Signal Transduct Target Ther. 2024 Sep 26;9(1):254.\|Small Methods. 2020 Dec 18.\|SSRN. 14 Feb 2022.\|SSRN. 2023 Sep 15.\|Toxins. 2023 Feb 6;15(2):132.\|Virology. 2024 Dec.\|Virus Res. 2020 Jan 15;276:197806.\|J Autoimmun. 2023 Mar 8;136:103012.
Smiles	O=C(C1=C(O)C=C2C=CC=CC2=C1)N/N=C/C3=CC=C(O)C(O)=C3
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	304448-55-3
Versandbedingung	Raumtemperatur
Lieferbar
Manufacturer - Type	Reference compound
Manufacturer - Applications	Metabolism-protein/nucleotide metabolism
Manufacturer - Targets	Autophagy; Dynamin; HSV; Virus Protease
Shipping Temperature	Room Temperature
Storage Conditions	-20°C, 3 years; 4°C, 2 years (Powder)
Molecular Weight	322.31
Product Description	Dynasore is a cell-permeable dynamin inhibitor with an IC50 of 15 μM. Dynasore blocks cell migration.
Manufacturer - Research Area	Metabolic Disease
Solubility	DMSO: 50 mg/mL (ultrasonic)
Manufacturer - Pathway	Anti-infection; Autophagy; Cytoskeleton
Isoform	HSV-1; HSV-2
Clinical information	No Development Reported

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HY-15304-10mM-safety-datasheet.pdf