Anti-H4K20me1 HIST1H4A Antibody

Store at -20°C. For long-term storage, store at -80°C. Avoid multiple freeze-thaw cycles.

Polyclonal

HIST1H4A

Histones are the main constituents of the protein part of chromosomes of eukaryotic cells. They are rich in the amino acids arginine and lysine and have been greatly conserved during evolution. Histones pack the DNA into tight masses of chromatin. Two core histones of each class H2A, H2B, H3 and H4 assemble and are wrapped by 146 base pairs of DNA to form one octameric nucleosome. Histone tails undergo numerous post-translational modifications, which either directly or indirectly alter chromatin structure to facilitate transcriptional activation or repression or other nuclear processes. In addition to the genetic code, combinations of the different histone modifications reveal the so-called “histone code”. Histone methylation and demethylation is dynamically regulated by respectively histone methyl transferases and histone demethylases.

Whole antiserum from rabbit containing 0.05% azide.

0.5-1 mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Histone H4

Boster Bio Anti-H4K20me1 HIST1H4A Antibody (Catalog# CI1005). Tested in ChIP, ELISA, Dot blot, WB applications. This antibody reacts with Human.

Belongs to the histone H4 family.