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Human UltraPro Mutant CD19 Protein (CD1-HM129)

ArtNr CD1-HM129-100UG
Hersteller KactusBio
Menge 100 ug
Quantity options 100 ug 500 ug
Kategorie
Format Liquid
Specific against Human (Homo sapiens)
Host HEK293
Konjugat/Tag HIS
Purity > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Dry ice Yes
Sequence Pro20-Pro278 with site mutations
Alias CD19,B4,CVID3,Leu-12,MGC12802
Versandbedingung Trockeneis
Lieferbar
Manufacturer - Type
Recombinant Protein
Manufacturer - Targets
CD19
Manufacturer - Conjugate / Tag
C-His
Shipping Temperature
Shipped with dry ice.
Storage Conditions
Valid for 12 months from date of receipt when stored at -80°C.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Molecular Weight
The protein has a predicted MW of 29.93 kDa. Due to glycosylation, the protein migrates to 45-60 kDa based on Bis-Tris PAGE result.
Description
Recombinant Human UltraPro Mutant CD19 Protein is expressed from HEK293 with His tag at the C-terminus.It contains Pro20-Pro278 with site mutations.
Background
CD19 is a 95 kDa transmembrane glycoprotein that plays a central role in B cell activation and humoral immune responses. Functions as coreceptor for the B-cell antigen receptor complex (BCR) on B-lymphocytes. Decreases the threshold for activation of downstream signaling pathways and for triggering B-cell responses to antigens. Activates signaling pathways that lead to the activation of phosphatidylinositol 3-kinase and the mobilization of intracellular Ca2 stores.
Endotoxin
Less than 0.1 EU per μg by the LAL method.
Formulation
Supplied as 0.22 μm filtered solution in PBS (pH 7.4).
Biotinylated
no

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ug
Lieferbar: In stock
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