Mouse Anti-Human CD300a Clone MEM-260 PE mAb

Hersteller Cell Sciences
Kategorie
Typ Antibody
Specific against Human
Clon MEM-260
Isotype IgG1
Applikationen FC
Menge 100 tests
Host Mouse
ArtNr CS-CMC412
Eclass 6.1 32160702
Eclass 9.0 32160702
Lieferbar
Applications
Flow Cytometry for analysis of human blood cells: working dilution of 20 ul reagent per 100 ul whole blood or 106 cells in a suspension. The content of a vial (2.0 ml) is sufficient for 100 tests. The optimal concentration should be determined by the user for each specific application.
Description
Mouse Anti-Human CD300a Clone MEM-260 Monoclonal Antibody conjugated to R-PE. CD300a (CMRF-35H, IRp60) is a non-MHC-specific inhibitory receptor of immunoglobulin superfamily, which contains three immunoreceptor tyrosine-based inhibitory motifs (ITIMs) that associate with SH2-containing phosphatases SHP-1 and SHP-2. CD300a is expressed on many cell types including T cells, NK cells, neutrophils, eosinophils or mast cells. Its triggering inhibits activating signals such as those of IL5, GM-CSF or eotaxin, as well as supresses mast cell degranulation or NK cell cytotoxic activity.
Formulation
Liquid in phosphate buffered saline (PBS) containing 15 mM sodium azide + 0.2% (w/v) BSA as a stabilizing agent.
Specificity
Reacts with CD300a, a 60 kDa leukocyte transmembrane glycoprotein expressed on human granulocytes, monocytes, neutrophils, NK cells, mast cells and dendritic cells, 25% of circulating T-cells and 15% of circulating B-cells.
Immunogen
HPB human acute lymphoid leukemia cell line
Storage and Stability
Store in the dark at 2-4C. Do not freeze. Avoid prolonged exposure to light. When stored as instructed, product is stable for one year.
Purity
The conjugate is purified by size-exclusion chromatography.
Menge: 100 tests
Lieferbar: In stock
Listenpreis: 555,15 €
Preis: 555,15 €
lieferbar

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Salesmanager: Arne Pelz

Email: sales@hoelzel.de

Arbeitsanleitung

CS-CMC412.pdf