Antibodies

Rabbit Anti-Human CASP1 Affinity Purified pAb

Hersteller Cell Sciences
Kategorie
Typ Antibody
Specific against Human
Isotype IgG
Applikationen WB, IF
Menge 100 ug
Host Rabbit
ArtNr CS-CMC433
Eclass 6.1 32160702
Eclass 9.0 32160702
Lieferbar
Applications
Western Blot Immunoprecipitation Immunofluorescence
Description
Rabbit Anti-Human Caspase 1 Affinity Purified polyclonal antibody. Caspase family of cysteine proteases has been shown to play a key role in apoptosis. Caspase 1 is the mammalian caspase responsible for the proteolytic conversion of the proforms of interleukin-1a and IL18 into active cytokines. Like other caspases, Caspase 1 itself is synthesized as a pro-enzyme that is cleaved during activation into large (20 kDa) and small (10 kDa) subunits. The cellular role of caspase 1 appears limited to cytokine activation as they do not have obvious roles in apoptosis.
Formulation
Liquid in PBS, pH 7.2 + 30% glycerol + 0.5% BSA + 0.01% thimerosal. Precaution: Thimerosal is a poisonous and hazardous substance which should be handled by trained staff only.
Specificity
Recognizes 45 kDa pro-caspase 1 and the 20 kDa cleaved product.
Immunogen
Synthetic peptide surrounding amino acid 132 of human caspase 1
Purification
Biospecific affinity chromatography
Storage and Stability
Store at -20C or in working aliquots at -80C for long term storage. Avoid repeated freeze-thaw cycles.
Cross-Reactivity
Reacts with human, mouse, and rat.
Menge: 100 ug
Lieferbar: In stock
Listenpreis: 913,60 €
Preis: 913,60 €
lieferbar

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Ihr Ansprechpartner:

Arne Pelz

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Arbeitsanleitung

CS-CMC433.pdf