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Rabbit Anti-Human CASP1 Affinity Purified pAb

Rabbit Anti-Human CASP1 Affinity Purified pAb

Manufacturer	Cell Sciences
Category	Neuroscience Molecular Targets for Neuroscience Aging & Neurological Disorders Neural Signaling Protein Aggregation, Clearance & Misfolding Antibodies Cell Biology Cell Status Apoptosis Western Blot Immunofluorescence Cardiovascular Research Ischemia & Reperfusion Injury Primary Antibodies
Type	Antibody Polyclonal
Specific against	Human
Isotype	IgG
Applications	WB
Amount	100 ug
Host	Rabbit
Item no.	CS-CMC433
Targets	CASP1, CTSB
eClass 6.1	32160702
eClass 9.0	32160702
Available
Cross-Reactivity	Reacts with human, mouse, and rat.
Description	Rabbit Anti-Human Caspase 1 Affinity Purified polyclonal antibody. Caspase family of cysteine proteases has been shown to play a key role in apoptosis. Caspase 1 is the mammalian caspase responsible for the proteolytic conversion of the proforms of interleukin-1a and IL18 into active cytokines. Like other caspases, Caspase 1 itself is synthesized as a pro-enzyme that is cleaved during activation into large (20 kDa) and small (10 kDa) subunits. The cellular role of caspase 1 appears limited to cytokine activation as they do not have obvious roles in apoptosis.
Formulation	Liquid in PBS, pH 7.2 + 30% glycerol + 0.5% BSA + 0.01% thimerosal. Precaution: Thimerosal is a poisonous and hazardous substance which should be handled by trained staff only.
Immunogen	Synthetic peptide surrounding amino acid 132 of human caspase 1
Purification	Biospecific affinity chromatography
Storage and Stability	Store at -20C or in working aliquots at -80C for long term storage. Avoid repeated freeze-thaw cycles.
Specificity	Recognizes 45 kDa pro-caspase 1 and the 20 kDa cleaved product.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

CS-CMC433.pdf

CS-CMC433-datasheet.pdf

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Amount: 100 ug

available

Delivery expected until 5/30/2024