Mouse Anti-Human IL-13 Clone B-B13 FITC mAb

FITC-conjugated Mouse Monoclonal Antibody against IL-13, Clone B-B13. IL-13 is an immunoregulatory cytokine produced primarily by activated Th2 cells. This cytokine is involved in several stages of B-cell maturation and differentiation. It up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. This cytokine down-regulates macrophage activity, thereby inhibiting the production of pro-inflammatory cytokines and chemokines. IL-13 is critical to the pathogenesis of allergen-induced asthma but operates through mechanisms independent of IgE and eosinophils. This antibody was produced, in vitro, using serum free medium.

Ion exchange chromatography.

Lyophilized product is stable for at least one year at 4C (expiration date is indicated on the vial). After reconstitution, the contents can be safely stored at 4C for one month or for one year at -20C. Add 0.02% sodium azide to prevent bacterial growth. Precaution: Sodium azide is a poisonous and hazardous substance which should be handled by trained staff only.