Antibodies

Mouse Anti-Human VEGFR-2/KDR Clone 4H3 mAb

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Hersteller Cell Sciences
Kategorie
Typ Antibody
Specific against Human
Clon 4H3
Isotype IgG1
Applikationen WB
Menge 100 ug
Host Mouse
ArtNr CS-CMV012
eClass 6.1 32160702
eClass 9.0 32160702
Lieferbar
Applications
Western Blot FACS analysis and cell sorting
Description
Mouse Anti-Human VEGFR-2/KDR Clone 4H3 monoclonal antibody. Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. VEGF recptor 2 is one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, and T-cell protein tyrosine phosphatase.
Formulation
Lyophilized from PBS, pH 7.2 without preservative.
Specificity
Detects Native Human KDR/VEGFR-2 on the surface of different human cell types.
Immunogen
Recombinant Human soluble extracellular KDR (D7)
Purification
Protein G chromatography
Reconstitution
Centrifuge vial prior to opening. Add sterile distilled water to a concentration of 0.1-1.0 mg/ml.
Storage and Stability
Stable at room temperature for up to one month. After reconstitution, stable for at least two weeks at 2-4C. Stable for at least 6 months when stored at -20C. Avoid repeated freeze-thaw cycles.
Application Notes
For western blot use at a working dilution of 2-5 ig/ml.For FACS use at a working dilution of 2-5 ig/ml.Optimal dilutions should be determined by each laboratory for each application.

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Menge: 100 ug
Lieferbar: In stock
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