Antibodies

Rabbit Anti-Human CASP8 pAb

Hersteller Cell Sciences
Kategorie
Typ Antibody
Specific against Human
Isotype IgG
Applikationen WB
Menge 100 ug
Host Rabbit
ArtNr CS-CPC129
Eclass 6.1 32160702
Eclass 9.0 32160702
Lieferbar
Applications
Western Blot
Description
Rabbit Anti-Mouse Caspase 8 polyclonal antibody. The caspase family of cysteine proteases has been shown to play a key role in apoptosis. Caspase 8 is a 55 kDa cytosolic protein that is synthesized as an inactive pro-enzyme. Activation of caspase 8 involves a two-step proteolysis: the cleavage of caspase 8 to generate a 43 and a 12 kDa fragment which is further processed to 10 kDa. The p43 is then cleaved to yield p26 and the release of the active site containing p18.
Formulation
Liquid in PBS, pH 7.2 + 30% glycerol + 0.5% BSA + 0.01% thimerosal. Precaution: Thimerosal is a poisonous and hazardous substance which should be handled by trained staff only.
Specificity
Detects the full length (55 kDa), intermediate cleavage fragments (26-31 kDa), and cleaved large fragment (18 kDa) of Caspase 8.
Immunogen
Synthetic peptide surrounding amino acid 392 of mouse Caspase 8
Purification
Protein A purified
Storage and Stability
Store at -20C or in working aliquots at -80C for long term storage. Avoid repeated freeze-thaw cycles .
Cross-Reactivity
Human, mouse, rat, cow, and monkey

Arbeitsanleitung

CS-CPC129.pdf

Menge: 100 ug
Lieferbar: In stock
Listenpreis: 901,84 €
Preis: 901,84 €
lieferbar

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Ihr Ansprechpartner:

Arne Pelz

sales@hoelzel.de