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Rabbit Anti-Human CASP8 pAb

Rabbit Anti-Human CASP8 pAb

Item no.	CS-CPC129
Manufacturer	Cell Sciences
Amount	100 ug
Category	Oncology Neuroscience Molecular Targets for Neuroscience Aging & Neurological Disorders Protein Aggregation, Clearance & Misfolding Antibodies By Cell Type Carcinoma Hematology Leukemia Lymphoma Cell Biology Cell Status Apoptosis Western Blot Cardiovascular Research Ischemia & Reperfusion Injury Primary Antibodies
Type	Antibody Polyclonal
Applications	WB
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	MCH5, CAP4, FLICE, MACH, apoptosis-related cysteine protease, ALPS2B, FLJ17672, MGC78473, FADD-homologous ICE/CED-3-like protease, MACH-alpha-1/2/3 protein, MACH-beta-1/2/3/4 protein, OTTHUMP00000163720, caspase 8, cysteine protease, Mch5 isoform alpha, OTTHUMP00000163718, OTTHUMP00000163719, procaspase-8
Available
Storage Conditions	Store at -20C or in working aliquots at -80C for long term storage. Avoid repeated freeze-thaw cycles .
Cross-Reactivity	Human, mouse, rat, cow, and monkey
Description	Rabbit Anti-Mouse Caspase 8 polyclonal antibody. The caspase family of cysteine proteases has been shown to play a key role in apoptosis. Caspase 8 is a 55 kDa cytosolic protein that is synthesized as an inactive pro-enzyme. Activation of caspase 8 involves a two-step proteolysis: the cleavage of caspase 8 to generate a 43 and a 12 kDa fragment which is further processed to 10 kDa. The p43 is then cleaved to yield p26 and the release of the active site containing p18.
Formulation	Liquid in PBS, pH 7.2 + 30% glycerol + 0.5% BSA + 0.01% thimerosal. Precaution: Thimerosal is a poisonous and hazardous substance which should be handled by trained staff only.
Immunogen	Synthetic peptide surrounding amino acid 392 of mouse Caspase 8
Purification	Protein A purified
Specificity	Detects the full length (55 kDa), intermediate cleavage fragments (26-31 kDa), and cleaved large fragment (18 kDa) of Caspase 8.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ug

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Delivery expected until 9/25/2025

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