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Recombinant Human 4-1BB Receptor

Recombinant Human 4-1BB Receptor

Hersteller	Cell Sciences
Kategorie	Oncology Neuroscience Neuroinflammation Metabolism Diabetes Peptides & Proteins Recombinant Proteins Cell Biology Obesity Cell Culture Cytokines Cell Status Necrosis Apoptosis
Typ	Proteins
Specific against	Human
Menge	20 ug
Host	E.coli
ArtNr	CS-CRB201B
Targets	TNF
eClass 6.1	34160400
eClass 9.0	42020190
Lieferbar
Biological Activity	Fully biologically active when compared to standard. The biological activity is measured by its binding ability in a functional ELISA. When Recombinant Human 4-1BB Receptor is immobilized at 10 ng/ml, the concentration of Recombinant Human 4-1BB Ligand that produces 50% optimal binding response is found to be approximately 0.5-2.5 ng/ml.
Description	Human 4-1BB Receptor, also named TNFRSF9, is a single non-glycosylated polypeptide chain containing 166 amino acids. 4-1BB Receptor is a member of the TNF superfamily of receptors. It is mainly expressed on the surface of a variety of T cells, but also found in B cells, monocytes, and various transformed cell lines. 4-1BB Receptor binds to 4-1BBL to provide a co-stimulatory signal for T lymphocytes. Signaling by 4-1BB Receptor has been implicated in the antigen-presentation process and generation of cytotoxic T cells.
Endotoxin Level	< 1 EU/ug as determined by LAL method.
Formulation	0.2 um sterile filtered and lyophilized in 10 mM PB, pH 8.0, + 150 mM NaCl.
Molecular Weight	17.7 kDa
Reconstitution	Centrifuge vial prior to opening. First add sterile distilled water to the vial to fully solubilize the protein to a concentration not less than 100 ug/ml. After complete solubilization of the protein, it can be further diluted to other aqueous solutions.
Storage and Stability	Store lyophilized protein at -20C to -80C. Reconstituted protein is stable for 1 week at 2-4C. For long term storage, aliquot and store at -20C to -80C with a carrier protein (0.1% HSA or BSA) as a stabilizer. This depends upon the particular application employed. Avoid repeated freeze-thaw cycles.

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