ArtNr |
CS-CRB201B |
Hersteller |
Cell Sciences
|
Menge |
20 ug |
Kategorie |
|
Typ |
Proteins |
Specific against |
Human (Homo sapiens) |
Host |
E.coli |
Purity |
>95.0% as determined by analysis by SDS-PAGE and HPLC. |
Sequence |
ERTRSLQDPC SNCPAGTFCD NNRNQICSPC PPNSFSSAGG QRTCDICRQC KGVFRTRKEC SSTSNAECDC TPGFHCLGAG CSMCEQDCKQ GQELTKKGCK DCCFGTFNDQ KRGICRPWTN CSLDGKSVLV NGTKERDVVC GPSPADLSPG ASSVTPPAPA REPGHS |
ECLASS 10.1 |
32160409 |
ECLASS 11.0 |
32160409 |
UNSPSC |
12352202 |
Similar products |
4-1BB, CD137, CDw137, ILA, MGC2172, 4-1BB ligand receptor, CD137 antigen, T cell antigen ILA, homolog of mouse 4-1BB, induced by lymphocyte activation (ILA), interleukin-activated receptor, T-cell antigen 4-1BB homolog, T-cell antigen ILA, tumor necrosis factor receptor superfamily member 9, receptor protein 4-1BB, homolog of mouse Ly63 |
Lieferbar |
|
Manufacturer - Category |
Biomolecules |
Storage Conditions |
Store lyophilized protein at -20C to -80C. Reconstituted protein is stable for 1 week at 2-4C. For long term storage, aliquot and store at -20C to -80C with a carrier protein (0.1% HSA or BSA) as a stabilizer. This depends upon the particular application employed. Avoid repeated freeze-thaw cycles. |
Molecular Weight |
17.7 kDa |
Description |
Human 4-1BB Receptor, also named TNFRSF9, is a single non-glycosylated polypeptide chain containing 166 amino acids. 4-1BB Receptor is a member of the TNF superfamily of receptors. It is mainly expressed on the surface of a variety of T cells, but also found in B cells, monocytes, and various transformed cell lines. 4-1BB Receptor binds to 4-1BBL to provide a co-stimulatory signal for T lymphocytes. Signaling by 4-1BB Receptor has been implicated in the antigen-presentation process and generation of cytotoxic T cells. |
Formulation |
0.2 um sterile filtered and lyophilized in 10 mM PB, pH 8.0, + 150 mM NaCl. |
Reconstitution |
Centrifuge vial prior to opening. First add sterile distilled water to the vial to fully solubilize the protein to a concentration not less than 100 ug/ml. After complete solubilization of the protein, it can be further diluted to other aqueous solutions. |
Biological Activity |
Fully biologically active when compared to standard. The biological activity is measured by its binding ability in a functional ELISA. When Recombinant Human 4-1BB Receptor is immobilized at 10 ng/ml, the concentration of Recombinant Human 4-1BB Ligand that produces 50% optimal binding response is found to be approximately 0.5-2.5 ng/ml. |
Endotoxin Level |
< 1 EU/ug as determined by LAL method. |
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