Vergleich

Recombinant Human NAP-2/CXCL7

ArtNr CS-CRN600C
Hersteller Cell Sciences
Menge 1.0 mg
Kategorie
Typ Proteins
Specific against Human (Homo sapiens)
Host E.coli
Purity >97% by HPLC and SDS-PAGE
Sequence AELRCMCIKT TSGIHPKNIQ SLEVIGKGTH CNQVEVIATL KDGRKICLDP DAPRIKKIVQ KKLAGDESAD
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Similar products NAP-2, TC1, PBP, member 7, beta-1, B-TG1, Beta-TG, CTAP-III, CTAP3, CTAPIII, CXCL7, LA-PF4, LDGF, MDGF, SCYB7, TC2, TGB, TGB1, THBGB, THBGB1, CXC chemokine ligand 7, beta-thromboglobulin, connective tissue-activating peptide III, leukocyte-derived growth factor, low-affinity platelet factor IV, macrophage-derived growth factor, neutrophil-activating peptide 2, neutrophil-activating peptide-2, platelet basic protein, pro-platelet basic protein, small inducible cytokine B7, small inducible cytokine subfamily B, thrombocidin 1, thrombocidin 2, thromboglobulin
Lieferbar
Manufacturer - Category
Biomolecules
Storage Conditions
Stable at 2-4C, but best kept desiccated -20C. Upon reconstitution, stable for up to 1 week at 2-4C. For longer term, store in working aliquots below -20C. Avoid repeated freeze/thaw cycles.
Molecular Weight
7.6 kDa
Description
Neutrophil Activating Peptide 2 (NAP-2) is proteolytically processed carboxyl-terminal fragments of platelet basic protein (PBP) which is found in the alpha-granules of human platelets. NAP-2 is a member of the CXC chemokines. Similar to other ELR domain containing CXC chemokines such as IL-8 and the GRO proteins, NAP-2 has been shown to bind CXCR-2 and to chemoattract and activate neutrophils. Although CTAP-III, beta-TG and PBP represent amino-terminal extended variants of NAP-2 and possess the same CXC chemokine domains, these proteins do not exhibit NAP-2 activity. Recently, it has been shown that the additional amino-terminal residues of CTAP-III masks the critical ELR receptor binding domain that is exposed on NAP-2 and may account for lack of NAP-2 activity.
Formulation
Lyophilized from a sterile filtered solution in 20 mM PB, pH 7.4 + 50 mM NaCl
Reconstitution
Centrifuge vial prior to opening. Add sterile distilled water or aqueous buffer to a concentration of 0.1-1.0 mg/ml. Further dilutions should be made in appropriate buffered solutions.
Biological Activity
Determined by the ability of NAP2 to chemoattract human neutrophils using a concentration of 1-10 ng/ml.
Endotoxin Level
Less than 1 EU/ug of rHuNAP-2/CXCL7 as determined by LAL method.

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Menge: 1.0 mg
Lieferbar: In stock
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