Synthetic Urobilinogen

Store at 2-4C, protect from air and light-protected under argon. SPECIAL PRECAUTIONS: Air and light sensitive. Keep Urobilinogen container tightly closed. After opening replace with nitrogen or argon pad. Minimize Urobilinogen exposure to air and light. Stable for 1 year. Do not freeze.

Urobilinogen is a bile pigment that is produced by the degradation of conjugated bilirubin in the biliary tree and small intestine. It is water soluble and colorless. Urobilinogen has several fates: partial oxidation to urobilin partial reabsoption in the small intestine and recirculation back to the liver-enterohepatic circulation reabsorption into blood and passage to kidney for excretion. Urobilinogen is present in the urine of normal subjects. If there is an increase in urobilinogen in the urine then this indicates hepato-cellular dysfunction or an increased bilirubin formation, e.g. due to hemolysis. In intrahepatic obstruction there is no urobilinogen in the urine. This Synthetic Urobilinogen is synthesized and used as an indicator in urine controls and test strips. Chemical Principle of Urine Test Strip: Modified Ehrlich's reaction. Urobilinogen present reacts with Ehrlich's reagent to form a red colored compound. Color changes from light orange-pink to dark pink. The test is based on a diazotization reaction of 4-Methoxybenzene diazoniurn salt and urinary urobilinogen in a strong acid medium. The color changes from pink to brown-red.

25 g/L (4 ml contains 100 mg)