Epetraborole (hydrochloride)

1234563-16-6

C11H17BClNO4

H2O : >= 28 mg/mL (102.37 mM)

Others

Epetraborole hydrochloride is a novel leucyl-tRNA synthetase (LeuRS) inhibitor, which inhibits protein synthesis by binding "to the terminal adenosine ribose (A76) of leucyl-tRNA synthetase". It is intended for the treatment of infections caused by Gram-negative bacteria. Epetraborole hydrochloride is a bacteriostatic compound that can against a wide range of anaerobic and Gram-negative bacteria, including multidrug-resistant pathogens, such as extended-spectrum-beta-lactamase-, metallo-beta-lactamase-, and carbapenemase-producing organism.