Theaflavin

4670-05-7

C29H24O12

DMSO : 1.42 mg/mL (2.52 mM; Need ultrasonic and warming); H2O : 2 mg/mL (3.54 mM; Need ultrasonic and warming)

Anti-infection

Theaflavin is a suitable natural inhibitor against influenza A (H1N1) neuraminidase. IC50 & Target: Influenza A (H1N1) virus^[1] In Vitro: Theaflavin, found in green tea, is observed to inhibit H1N1 NA proteins strongly supported by lowest docking energy. Theaflavin is a plant product traditionally used for treatment of influenza infection. Green tea is particularly rich in polyphenolic compounds like Theaflavin. Theaflavin derivatives have shown pronounced antiviral activity. Theaflavin is found to interact with the amino acid residues like Arg118, Asp151, Asp 152, Arg193, Asp199, Asn344, and Arg430 of NA by forming hydrogen bonds^[1].