Dihydrorhodamine 123

109244-58-8

C21H18N2O3

10 mM in DMSO

Others

Dihydrorhodamine 123 is a fluorescent probe (lambda_ex=488 nm, lambda_em=525 nm). In Vitro: In the presence of 10 uM Dihydrorhodamine 123 (DHR) the stimulation of the neutrophil NADPH oxidase by the addition of 50 nM phorbol 12-myristate 13-acetat (PMA) resultes in an increase in the rate of rhodamine generation. The fluorescent intensity of the cells, in the presence of 10 uM Dihydrorhodamine 123, increases with time following the addition of 50 nM PMA. In the presence of 10 uM Dihydrorhodamine 123, induced HL60 cells show a sustained increase in fluorescence following the addition of 50 nM PMA^[1].