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Recombinant Rat Interleukin 4 (a. a. 126) Polypeptide

Recombinant Rat Interleukin 4 (a. a. 126) Polypeptide

ArtNr	DAG335
Hersteller	Creative Diagnostics
Menge	10 ug
Kategorie	Oncology Peptides & Proteins Cell Biology Cell Culture Cytokines Peptides By Organ Heart & Blood Cancer Thyroid Cancer
Typ	Peptides
Format	Lyophilized
Specific against	other
Purity	>98% pure(HPLC and SDS-PAGE). Endotoxin level is less than 0.1ng/ug (IEU/ug). Purifiedby chromatographic techniques. Product is sterile filtered.
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Il4,interleukin 4,Il4e12,interleukin-4,IL-4,BSF-1,B-cell growth factor 1,B-cell stimulatory factor 1,lymphocyte stimulatory factor 1,B-cell IGGdifferentiation factor,BCGF-1,BCGF1,BSF1,MGC79402,B cell growth factor1,binetrakin,pitrakinra,Binetrakin,Pitrakinra,B cell IgG differentiationfactor,B Cell Stimulatory Factor 1,IGG1 induction factor
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Manufacturer - Applications	The ED50 asdetermined by dose-dependent proliferation of Con A activated rat spleencells is <1.5ng/ml, corresponding to a specific activity of 6.6 x 105IU/mg. Each laboratory should determine an optimum working titer for use inits particular application. Other applications have not been tested but usein such assays should not necessarily be excluded.
Storage Conditions	The lyophilized product, thoughstable for 3 weeks at room temperature, is best stored at –20°C. Afterreconstitution, short term (up to 1 week) store at 2-8oC. Long term, add 0.1%HSA or BSA, aliquot and store at –20°C. Avoid multiple freeze/thaw cycles.
Full name	Interleukin 4
Product Overview	Recombinant Rat IL-4is a single, non-glycosylated polypeptide chain containing 126 amino acidsand having a molecular weight of 14, 105 Da. The sequence of the first fiveN-terminal amino acids was determined to be Met-His-Gly-Cys-Asn. Containsless than 1% dimers and aggregates.
Abbr	Il4 (a.a. 126)
Manufacturer - Format	Purified, Lyophilized, Reconstitute using sterile deionized water to a concentration >100ug/ml.Further dilutions can be made in other aqueous buffers.
Buffer	Water containing no additives
Concentration	1mg/ml (OD280nm, E0.1% = 0.2) (prior to lyophilization)
Preservative	None
Gene Information - Gene Name	Il4 interleukin 4 [ Rattusnorvegicus ]
Gene Information - mRNA Refseq	NM_201270
Gene Information - Protein Refseq	NP_958427
Gene Information - Pathway	Allograft rejection, Autoimmune thyroid disease, Cytokine-cytokine receptor interaction, Cytokinesand Inflammatory Response (BioCarta), Fc epsilon RI signaling pathway, Hematopoietic cell lineage, IL-4 Signaling Pathway, Intestinal immune networkfor IgA production, Jak-STAT signaling pathway, T cell receptor signalingpathway
Gene Information - Function	cytokine activity, growth factor activity, interleukin-4 receptor binding
Antigen Description	Interleukin-4, abbreviated IL-4, is a cytokine that induces differentiation of naive helperT cells (Th0 cells) to Th2 cells. Upon activation by IL-4, Th2 cellssubsequently produce additional IL-4. The cell that initially produces IL-4, thus inducing Th0 differentiation, has not been identified, but recentstudies suggest that basophils may be the effector cell. It is closelyrelated and has functions similar to Interleukin 13.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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Menge: 10 ug

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Lieferung vsl. bis 18.12.2025