Comparison

Recombinant Rat Interleukin 4 (a. a. 126) Polypeptide

Item no. DAG335
Manufacturer Creative Diagnostics
Amount 10 ug
Category
Type Peptides
Format Lyophilized
Specific against other
Purity >98% pure(HPLC and SDS-PAGE). Endotoxin level is less than 0.1ng/ug (IEU/ug). Purifiedby chromatographic techniques. Product is sterile filtered.
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias Il4,interleukin 4,Il4e12,interleukin-4,IL-4,BSF-1,B-cell growth factor 1,B-cell stimulatory factor 1,lymphocyte stimulatory factor 1,B-cell IGGdifferentiation factor,BCGF-1,BCGF1,BSF1,MGC79402,B cell growth factor1,binetrakin,pitrakinra,Binetrakin,Pitrakinra,B cell IgG differentiationfactor,B Cell Stimulatory Factor 1,IGG1 induction factor
Available
Manufacturer - Applications
The ED50 asdetermined by dose-dependent proliferation of Con A activated rat spleencells is <1.5ng/ml, corresponding to a specific activity of 6.6 x 105IU/mg. Each laboratory should determine an optimum working titer for use inits particular application. Other applications have not been tested but usein such assays should not necessarily be excluded.
Storage Conditions
The lyophilized product, thoughstable for 3 weeks at room temperature, is best stored at –20°C. Afterreconstitution, short term (up to 1 week) store at 2-8oC. Long term, add 0.1%HSA or BSA, aliquot and store at –20°C. Avoid multiple freeze/thaw cycles.
Full name
Interleukin 4
Product Overview
Recombinant Rat IL-4is a single, non-glycosylated polypeptide chain containing 126 amino acidsand having a molecular weight of 14, 105 Da. The sequence of the first fiveN-terminal amino acids was determined to be Met-His-Gly-Cys-Asn. Containsless than 1% dimers and aggregates.
Abbr
Il4 (a.a. 126)
Manufacturer - Format
Purified, Lyophilized, Reconstitute using sterile deionized water to a concentration >100ug/ml.Further dilutions can be made in other aqueous buffers.
Buffer
Water containing no additives
Concentration
1mg/ml (OD280nm, E0.1% = 0.2) (prior to lyophilization)
Preservative
None
Gene Information - Gene Name
Il4 interleukin 4 [ Rattusnorvegicus ]
Gene Information - mRNA Refseq
NM_201270
Gene Information - Protein Refseq
NP_958427
Gene Information - Pathway
Allograft rejection, Autoimmune thyroid disease, Cytokine-cytokine receptor interaction, Cytokinesand Inflammatory Response (BioCarta), Fc epsilon RI signaling pathway, Hematopoietic cell lineage, IL-4 Signaling Pathway, Intestinal immune networkfor IgA production, Jak-STAT signaling pathway, T cell receptor signalingpathway
Gene Information - Function
cytokine activity, growth factor activity, interleukin-4 receptor binding
Antigen Description
Interleukin-4, abbreviated IL-4, is a cytokine that induces differentiation of naive helperT cells (Th0 cells) to Th2 cells. Upon activation by IL-4, Th2 cellssubsequently produce additional IL-4. The cell that initially produces IL-4, thus inducing Th0 differentiation, has not been identified, but recentstudies suggest that basophils may be the effector cell. It is closelyrelated and has functions similar to Interleukin 13.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 10 ug
Available: In stock
available

Delivery expected until 12/18/2025 

Compare

Add to wishlist

Get an offer

Request delivery time

Ask a technical question

Submit a bulk request

Questions about this Product?
 
Close