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Recombinant Human Thyroid Peroxidase

ArtNr DAG265
Hersteller Creative Diagnostics
Menge 100 ug
Kategorie
Typ Proteins Recombinant
Format Lyophilized
Applikationen ELISA
Specific against other
Purity >=95% pure (SDS-PAGE). Affinity purification using a monoclonal antibody and ion exchange chromatography
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias MSA,TPX,TDH2A,thyroid peroxidase,thyroperoxidase,OTTHUMP00000115303,OTTHUMP00000115304,OTTHUMP00000115535,OTTHUMP00000115536,thyroid microsomal antigen
Lieferbar
Manufacturer - Applications
Suitablefor use in ELISA and Western blot. Each laboratory should determine anoptimum working titer for use in its particular application. Otherapplications have not been tested but use in such assays should notnecessarily be excluded.
Storage Conditions
Store lyophilized product at -20°C. After reconstitution, aliquot and store at-70°C. Avoid multiple freeze/thaw cycles.
Full name
Thyroid Peroxidase
Product Overview
Recombinantsoluble extracellular domain of human thyroid peroxidase (amino acids19-846). Does not contain a fusion partner. Molecular weight is 91, 981 Da.Immunoreactive in ELISA with human anti-TPO autoantibodies.
Abbr
TPO (Human)
Manufacturer - Format
Affinity Purified, Lyophilized, Reconstitute with deionized water.
Buffer
Lyophilizedfrom 20mM Tris-HCl, pH 8.0 containing 250mM Sodium chloride, 0.1mM KI and 5%D-mannitol
Concentration
Not applicable
Preservative
None
Gene Information - Gene Name
TPOthyroid peroxidase [ Homo sapiens ]
Gene Information - mRNA Refseq
NM_000547
Gene Information - Protein Refseq
NP_000538
Gene Information - MIM
606765
Gene Information - Pathway
Amine-derived hormones, Biosynthesis ofamine and peptide hormones, Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, Jak-STAT signaling pathway, Metabolism ofhormones, Thyroxine biosynthesis
Gene Information - Function
calcium ion binding, iodide peroxidase activity, heme binding, oxidoreductase activity, peroxidaseactivity
Antigen Description
Thyroidperoxidase or thyroperoxidase (TPO) is an enzyme expressed mainly in thethyroid that liberates iodine for addition onto tyrosine residues onthyroglobulin for the production of thyroxine (T4) or triiodothyronine (T3), thyroid hormones. In humans, thyroperoxidase is encoded by the TPO gene.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ug
Lieferbar: In stock
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