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Recombinant Human Thyroid Peroxidase

Recombinant Human Thyroid Peroxidase

Item no.	DAG265
Manufacturer	Creative Diagnostics
Amount	100 ug
Category	Oncology Peptides & Proteins Recombinant Proteins Cell Biology Cell Metabolism ELISA By Organ Thyroid Cancer Immunostaining
Type	Proteins Recombinant
Format	Lyophilized
Applications	ELISA
Specific against	other
Purity	>=95% pure (SDS-PAGE). Affinity purification using a monoclonal antibody and ion exchange chromatography
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	MSA,TPX,TDH2A,thyroid peroxidase,thyroperoxidase,OTTHUMP00000115303,OTTHUMP00000115304,OTTHUMP00000115535,OTTHUMP00000115536,thyroid microsomal antigen
Available
Manufacturer - Applications	Suitablefor use in ELISA and Western blot. Each laboratory should determine anoptimum working titer for use in its particular application. Otherapplications have not been tested but use in such assays should notnecessarily be excluded.
Storage Conditions	Store lyophilized product at -20°C. After reconstitution, aliquot and store at-70°C. Avoid multiple freeze/thaw cycles.
Full name	Thyroid Peroxidase
Product Overview	Recombinantsoluble extracellular domain of human thyroid peroxidase (amino acids19-846). Does not contain a fusion partner. Molecular weight is 91, 981 Da.Immunoreactive in ELISA with human anti-TPO autoantibodies.
Abbr	TPO (Human)
Manufacturer - Format	Affinity Purified, Lyophilized, Reconstitute with deionized water.
Buffer	Lyophilizedfrom 20mM Tris-HCl, pH 8.0 containing 250mM Sodium chloride, 0.1mM KI and 5%D-mannitol
Concentration	Not applicable
Preservative	None
Gene Information - Gene Name	TPOthyroid peroxidase [ Homo sapiens ]
Gene Information - mRNA Refseq	NM_000547
Gene Information - Protein Refseq	NP_000538
Gene Information - MIM	606765
Gene Information - Pathway	Amine-derived hormones, Biosynthesis ofamine and peptide hormones, Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, Jak-STAT signaling pathway, Metabolism ofhormones, Thyroxine biosynthesis
Gene Information - Function	calcium ion binding, iodide peroxidase activity, heme binding, oxidoreductase activity, peroxidaseactivity
Antigen Description	Thyroidperoxidase or thyroperoxidase (TPO) is an enzyme expressed mainly in thethyroid that liberates iodine for addition onto tyrosine residues onthyroglobulin for the production of thyroxine (T4) or triiodothyronine (T3), thyroid hormones. In humans, thyroperoxidase is encoded by the TPO gene.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ug

available

Delivery expected until 12/18/2025

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