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Recombinant Human Interleukin 15 (a. a. 114)

ArtNr DAG354
Hersteller Creative Diagnostics
Menge 10 ug
Kategorie
Typ Proteins Recombinant
Format Lyophilized
Specific against other
Purity >98%pure (SDS-PAGE and HPLC analysis). Endotoxin level is <0.1ng per ug(1EU/ug). Product is 0.2um filtered.
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias IL15,interleukin 15,IL-15,MGC9721,interleukin-15,OTTHUMP00000164616,OTTHUMP00000164617,OTTHUMP00000218093,OTTHUMP00000228804,OTTHUMP00000228805,IL 15,Interleukin15
Lieferbar
Manufacturer - Applications
The ED50as determined by the dose-dependent proliferation of murine CTLL-2cells was found to be <0.5ng/ml, corresponding to a specificactivity of >2 x106 units/mg. Each laboratory shoulddetermine an optimum working titer for use in its particular application.Other applications have not been tested but use in such assays should notnecessarily be excluded.
Storage Conditions
Thelyophilized product, though stable at room temperature, is best stored -20°C.After reconstitution, aliquot and store at –20°C. Avoid multiple freeze/thawcycles.
Full name
Interleukin 15
Product Overview
IL-15 isan immunomodulating cytokine that stimulates the proliferation of Tlymphocytes and shares many biological properties with IL-2. IL-15 exerts itsbiological activities primarily on T cells. It is also essential in thedevelopment, survival and activation of NK cells. Recombinant human IL-15which was expressed in E. coli is a 12.9kDa protein consisting of 114 aminoacid residues.
Abbr
IL15 (a.a. 114)
Manufacturer - Format
Purified, Lyophilized. We recommend a quick spin followed by reconstitution in water toa concentration of 0.1-1.0mg/ml. This solution can then be diluted into otheraqueous buffers and stored (up to 1 week) at 2-8C or stored at –20C forfuture use.
Buffer
Lyophilized from10mM Sodium phosphate, pH 8.5
Concentration
Not applicable
Preservative
None
Gene Information - Gene Name
IL15interleukin 15 [ Homo sapiens ]
Gene Information - mRNA Refseq
NM_000585
Gene Information - Protein Refseq
NP_000576
Gene Information - MIM
600554
Gene Information - Pathway
Cytokine-cytokinereceptor interaction, HTLV-I infection, Herpes simplex infection, Intestinalimmune network for IgA production, Jak-STAT signaling pathway, Rheumatoidarthritis
Gene Information - Function
cytokine activity, cytokine receptor binding, protein binding, signal transducer activity
Antigen Description
Interleukin15 (IL-15) is a cytokine with structural similarity to IL-2. Like IL-2, IL-15binds to and signals through the IL-2/IL-15 beta chain (CD122) and the commongamma chain (gamma-C, CD132). IL-15 is secreted by mononuclear phagocytes(and some other cells) following infection by virus(es). This cytokineinduces cell proliferation of natural killer cells, cells of the innateimmune system whose principal role is to kill virally infected cells.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 10 ug
Lieferbar: In stock
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Lieferung vsl. bis 18.12.2025 

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